Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: 3-Desmethylcolchicine
RN: 7336-33-6
UNII: C939KS8QEL
InChIKey: JRRUSQGIRBEMRN-HNNXBMFYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C21-H23-N-O6

Molecular Weight

  • 385.4137
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • 3-Desmethylcolchicine

Synonyms

  • 3-Demethylcolchicine
  • 3-Desmethylcolchicine
  • 3-O-Demethylcolchicine
  • Acetamide, N-(5,6,7,9-tetrahydro-3-hydroxy-1,2,10-trimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)
  • Benzoheptalen-9(5H)-one, 7-acetamido-6,7-dihydro-, L-
  • Colchiciine, 3-desmethyl-
  • Colchicine, 2-demethyl-
  • Colchicine, O(sup 3)-demethyl-
  • Desmethylcolchicine
  • NSC 172946
  • NSC 50164
  • O3-Demethyl colchicine
  • O3-Demethylcolchicine
  • UNII-C939KS8QEL

Systematic Names

  • Acetamide, N-(5,6,7,9-tetrahydro-3-hydroxy-1,2,10-trimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)- (9CI)
  • Colchicine, 3-O-demethyl-
  • Colchicine, O(3)-demethyl- (8CI)
  • N-(5,6,7,9-Tetrahydro-3-hydroxy-1,2,10-trimethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide (S)- (9CI)

Registry Numbers

CAS Registry Number

  • 7336-33-6

FDA UNII

  • C939KS8QEL

Other Registry Number

  • 76265-64-0

System Generated Number

  • 0007336336

Structure Descriptors

InChI

1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-17(25)20(27-3)21(28-4)19(12)13-6-8-18(26-2)16(24)10-14(13)15/h6,8-10,15,25H,5,7H2,1-4H3,(H,22,23)/t15-/m0/s1

InChIKey

JRRUSQGIRBEMRN-HNNXBMFYSA-N

Smiles

COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(O)c(OC)c(OC)c23)NC(=O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 570ug/kg (0.57mg/kg)   Journal of Medicinal Chemistry. Vol. 24, Pg. 636, 1981.