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Substance Name: HEPES
RN: 7365-45-9
UNII: RWW266YE9I
InChIKey: JKMHFZQWWAIEOD-UHFFFAOYSA-N

Note

  • A dipolar ionic buffer.

Classification Code

  • Buffers

Molecular Formula

  • C8-H18-N2-O4-S

Molecular Weight

  • 238.3062
 
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Names and Synonyms

Name of Substance

  • HEPES

MeSH Heading

  • HEPES

Synonyms

  • 4-(2-Hydroxyethyl)-1-piperazineethane sulfonic acid
  • 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid
  • 5-23-02-00379 (Beilstein Handbook Reference)
  • BRN 0883043
  • EC 230-907-9
  • EINECS 230-907-9
  • HEPES
  • N-2-Hydroxyethylpiperazine N',2'-ethanesulfonic acid
  • N-2-Hydroxyethylpiperazine-N'-ethanesulfonate
  • N-2-Hydroxyethylpiperazine-N'-ethanesulfonic acid
  • N-2-Hydroxyethylpiperazine-N-ethane sulfonic acid
  • NSC 166663
  • UNII-RWW266YE9I

Systematic Names

  • 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-
  • 4-(2-Hydroxyethyl)piperazin-1-ylethanesulphonic acid

Registry Numbers

CAS Registry Number

  • 7365-45-9

FDA UNII

  • RWW266YE9I

Related Registry Number

  • 75277-39-3 (mono-hydrochloride salt)

System Generated Number

  • 0007365459

Structure Descriptors

InChI

1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)

InChIKey

JKMHFZQWWAIEOD-UHFFFAOYSA-N

Smiles

S(CCN1CC[NH+](CCO)CC1)(=O)(=O)[O-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
quail LD50 oral > 316mg/kg (316mg/kg)   Ecotoxicology and Environmental Safety. Vol. 6, Pg. 149, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 234 deg C   EXP
pKa Dissociation Constant 3 (none)   EXP
log P (octanol-water) -4.070 (none)   EST
Atmospheric OH Rate Constant 2.02E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.