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Substance Name: Indecainide hydrochloride [USAN]
RN: 73681-12-6
UNII: M76V0B96L5
InChIKey: NXNSCUZKMVYAJQ-UHFFFAOYSA-N

Classification Codes

  • Cardiac Depressant (Anti-Arrhythmic)
  • Drug / Therapeutic Agent

Molecular Formula

  • C20-H24-N2-O.Cl-H

Molecular Weight

  • 344.884
 
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Names and Synonyms

Name of Substance

  • Indecainide hydrochloride
  • Indecainide hydrochloride [USAN]

Synonyms

  • 9-(3-((1-Methylethyl)amino)propyl)-9H-fluorene-9-carboxamide hydrochloride
  • 9-(3-(Isopropylamino)propyl)fluorene-9-carboxamide monohydrochloride
  • 9H-Fluorene-9-carboxamide, 9-(3-((1-methylethyl)amino)propyl)-, monohydrochloride
  • Decabid
  • Indecainide HCl
  • Indecainide hydrochloride
  • LY 135837
  • UNII-M76V0B96L5

Systematic Name

  • 9H-Fluorene-9-carboxamide, 9-(3-((1-methylethyl)amino)propyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 73681-12-6

FDA UNII

  • M76V0B96L5

Related Registry Number

  • 74517-78-5 (Parent)

System Generated Number

  • 0073681126

Molecular Formulas

Molecular Formula

  • C20-H24-N2-O.Cl-H

Molecular Formula Fragments

  • C20-H24-N2-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C20H24N2O.ClH/c1-14(2)22-13-7-12-20(19(21)23)17-10-5-3-8-15(17)16-9-4-6-11-18(16)20;/h3-6,8-11,14,22H,7,12-13H2,1-2H3,(H2,21,23);1H

InChIKey

NXNSCUZKMVYAJQ-UHFFFAOYSA-N

Smiles

C1(c2c(cccc2)c2c1cccc2)(CCCNC(C)C)C(N)=O.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 5mg/kg (5mg/kg)   Toxicology Letters. Vol. 26, Pg. 107, 1985.
dog LD50 oral 25mg/kg (25mg/kg)   Fundamental and Applied Toxicology. Vol. 5, Pg. 175, 1985.
monkey LD50 oral > 50mg/kg (50mg/kg)   Fundamental and Applied Toxicology. Vol. 5, Pg. 175, 1985.
mouse LD50 oral 96mg/kg (96mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Fundamental and Applied Toxicology. Vol. 5, Pg. 175, 1985.
rat LD50 intravenous 10mg/kg (10mg/kg)   Toxicology Letters. Vol. 26, Pg. 107, 1985.
rat LD50 oral 82mg/kg (82mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE WEAKNESS
Fundamental and Applied Toxicology. Vol. 5, Pg. 175, 1985.