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Substance Name: Morphinan-14-ol, 4,5-alpha-epoxy-3-methoxy-17-methyl-
RN: 7387-55-5
InChIKey: RTSADQCTRAIWTC-LTCOOKNTSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C18-H23-N-O3

Molecular Weight

  • 301.384
 
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Names and Synonyms

Synonyms

  • 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-14-ol
  • BRN 0623758
  • RAM-306

Systematic Name

  • Morphinan-14-ol, 4,5-alpha-epoxy-3-methoxy-17-methyl-

Registry Numbers

CAS Registry Number

  • 7387-55-5

System Generated Number

  • 0007387555

Structure Descriptors

InChI

1S/C18H23NO3/c1-19-9-8-17-14-4-3-7-18(17,20)13(19)10-11-5-6-12(21-2)16(22-14)15(11)17/h5-6,13-14,20H,3-4,7-10H2,1-2H3/t13-,14+,17-,18-/m1/s1

InChIKey

RTSADQCTRAIWTC-LTCOOKNTSA-N

Smiles

O[C@]12[C@H]3Cc4c5c(c(OC)cc4)O[C@H]([C@@]15CC[N@@]3C)CCC2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 45600ug/kg (45.6mg/kg) PERIPHERAL NERVE AND SENSATION: LOCAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Yakugaku Zasshi. Journal of Pharmacy. Vol. 84, Pg. 268, 1964.