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Substance Name: Methyl chloride
RN: 74-87-3
UNII: A6R43525YO
InChIKey: NEHMKBQYUWJMIP-UHFFFAOYSA-N

Note

  • A hydrocarbon used as an industrial solvent. It has been used as an aerosal propellent, as a refrigerant and as a local anesthetic. (From Martindale, The Extra Pharmacopoeia, 31st ed, p1403)

Molecular Formula

  • C-H3-Cl

Molecular Weight

  • 50.4877
 

Classification Codes

Classification Codes

  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Tumor Data
  • Unspecified / Unclassified Pesticide

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 193
  • 2011 CERCLA Priority List, Rank: 189
  • Overall Carcinogenic Evaluation: Group 3
  • Reportable Quantity (RQ) = 100 lb
  • TWA (50 ppm); STEL (100 ppm); skin; Not classifiable as a human carcinogen
  • TWA 100 mg/m3; Ceiling 200 mg/m3, peak 300 mg/m3 in 5 min in any

Names and Synonyms

Name of Substance

  • Methyl chloride

MeSH Heading

  • Methyl chloride

Synonyms

  • AI3-01707
  • Artic
  • Caswell No. 557
  • CCRIS 1124
  • Chloor-methaan
  • Chloor-methaan [Dutch]
  • Chlor-methan
  • Chlor-methan [German]
  • Chloromethane
  • Chlorure de methyle
  • Chlorure de methyle [French]
  • Clorometano
  • Clorometano [Italian]
  • Cloruro di metile
  • Cloruro di metile [Italian]
  • EC 200-817-4
  • EINECS 200-817-4
  • EPA Pesticide Chemical Code 053202
  • HSDB 883
  • Methane, chloro-
  • Methyl chloride
  • Methylchlorid
  • Methylchlorid [German]
  • Methylchloride
  • Metylu chlorek
  • Metylu chlorek [Polish]
  • Monochloromethane
  • R 40
  • RCRA waste number U045
  • UNII-A6R43525YO

Systematic Names

  • Chloromethane
  • Methane, chloro-
  • Methyl chloride

Superlist Names

  • Chloromethane
  • Methane, chloro-
  • Methyl chloride
  • Methyl chloride, or Refrigerant gas R 40
  • Methyl chloride, or Refrigerant gas R 40 [UN1063] [Flammable gas]
  • RCRA waste no. U045
  • UN1063

Registry Numbers

CAS Registry Number

  • 74-87-3

FDA UNII

  • A6R43525YO

Other Registry Numbers

  • 1173018-35-3
  • 1474045-09-4
  • 1474045-10-7
  • 1474045-11-8
  • 16786-44-0

System Generated Number

  • 0000074873

Structure Descriptors

InChI

1S/CH3Cl/c1-2/h1H3

InChIKey

NEHMKBQYUWJMIP-UHFFFAOYSA-N

Smiles

CCl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 129mg/m3/4H (129mg/m3) BEHAVIORAL: GENERAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Archiv fuer Hygiene und Bakteriologie. Vol. 116, Pg. 131, 1936.
dog LCLo inhalation 14661ppm/6H (14661ppm) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
National Institutes of Health, Bulletin. Vol. 191, Pg. 1, 1949.
guinea pig LCLo inhalation 20000ppm/2H (20000ppm)   Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967.
human LCLo inhalation 20000ppm/2H (20000ppm) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 386, 1969.
mouse LC50 inhalation 2200ppm/6H (2200ppm)   Toxicology and Applied Pharmacology. Vol. 86, Pg. 93, 1986.
rat LC50 inhalation 5300mg/m3/4H (5300mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 82, 1982.
rat LD50 oral 1800mg/kg (1800mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 86, 1986.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -9.77E+01 deg C   EXP
Boiling Point -2.40E+01 deg C   EXP
log P (octanol-water) 0.91 (none)   EXP
Water Solubility 5320 mg/L 25 EXP
Vapor Pressure 4300 mm Hg 25 EXP
Henry's Law Constant 0.00882 atm-m3/mole 24 EXP
Atmospheric OH Rate Constant 4.36E-14 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.