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Substance Name: Hydrogen cyanide [ISO]
RN: 74-90-8
UNII: 2WTB3V159F
InChIKey: LELOWRISYMNNSU-UHFFFAOYSA-N

Note

  • Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.

Molecular Formula

  • C-H-N

Molecular Weight

  • 27.0259
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Chemical Warfare Agents
  • Fungicide, Bactericide, Wood Preservative
  • Human Data
  • Insecticide
  • Noxae
  • Poisons

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 133
  • 2011 CERCLA Priority List, Rank: 137
  • Ceiling (4.7 ppm); skin
  • Reportable Quantity (RQ) = 10 lb
  • Threshold Planning Quantity (TPQ) = 100 lb
  • TWA 10 ppm (11 mg/m3); skin

Names and Synonyms

Results Name

  • Hydrogen cyanide [ISO]

Name of Substance

  • Hydrogen cyanide

MeSH Heading

  • Hydrogen cyanide

Synonyms

  • 4-02-00-00050 (Beilstein Handbook Reference)
  • AC [Cyanide]
  • Acide cyanhydrique
  • Acide cyanhydrique [French]
  • Acide cyanhydrique [ISO-French]
  • Acido cianidrico
  • Acido cianidrico [Italian]
  • Aero Liquid HCN
  • Agent AC
  • AI3-31100-X
  • Blausaeure
  • Blausaeure [German]
  • Blauwzuur
  • Blauwzuur [Dutch]
  • BRN 1718793
  • Carbon hydride nitride (CHN)
  • Caswell No. 483
  • Cyaanwaterstof
  • Cyaanwaterstof [Dutch]
  • Cyanwasserstoff
  • Cyanwasserstoff [German]
  • Cyclon
  • Cyclone B
  • Cyjanowodor
  • Cyjanowodor [Polish]
  • EC 200-821-6
  • EINECS 200-821-6
  • EPA Pesticide Chemical Code 045801
  • Evercyn
  • Formic anammonide
  • Formonitrile
  • HCN
  • HSDB 165
  • Hydrocyanic acid
  • Hydrogen cyanide
  • Hydrogen cyanide [ISO]
  • Prussic acid
  • RCRA waste number P063
  • UN 1051
  • UNII-2WTB3V159F
  • Zaclondiscoids
  • Zyklon B

Systematic Names

  • Hydrocyanic acid
  • Hydrogen cyanide

Superlist Names

  • Hydrocyanic acid
  • Hydrocyanic acid (prussic), unstabilized
  • Hydrocyanic acid (prussic), unstabilized [Forbidden]
  • Hydrocyanic acid aqueous solutions, with not >20% hydrocyanic acid
  • Hydrocyanic acid, anhydrous, stabilized
  • Hydrocyanic acid, anhydrous, stabilized, absorbed in a porous inert material
  • Hydrocyanic acid, aqueous solutions <5% hydrogen cyanide
  • Hydrocyanic acid, aqueous solutions <5% hydrogen cyanide [NA1613] [Poison]
  • Hydrocyanic acid, aqueous solutions or Hydrogen cyanide, aqueous solutions with not > 20% hydrogen cyanide
  • Hydrocyanic acid, aqueous solutions or Hydrogen cyanide, aqueous solutions with not > 20% hydrogen cyanide [UN1613] [Poison]
  • Hydrogen cyanide
  • Hydrogen cyanide, anhydrous, stabilized
  • Hydrogen cyanide, anhydrous, stabilized, absorbed in a porous inert material
  • Hydrogen cyanide, solution in alcohol with not >45% hydrogen cyanide
  • Hydrogen cyanide, solution in alcohol with not >45% hydrogen cyanide [UN3294] [Poison]
  • Hydrogen cyanide, stabilized with <3% water
  • Hydrogen cyanide, stabilized with <3% water [UN1051] [Poison]
  • Hydrogen cyanide, stabilized, with <3% water and absorbed in a porous inert material
  • Hydrogen cyanide, stabilized, with <3% water and absorbed in a porous inert material [UN1614] [Poison]
  • NA1613
  • Prussic acid, anhydrous, stabilized
  • Prussic acid, anhydrous, stabilized, absorbed in a porous inert material
  • RCRA waste no. P063
  • UN1051
  • UN1613
  • UN1614
  • UN3294

Registry Numbers

CAS Registry Number

  • 74-90-8

FDA UNII

  • 2WTB3V159F

Other Registry Numbers

  • 191234-22-7
  • 341972-31-4

System Generated Number

  • 0000074908

Structure Descriptors

InChI

1S/CHN/c1-2/h1H

InChIKey

LELOWRISYMNNSU-UHFFFAOYSA-N

Smiles

C#N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - domestic LDLo oral 600ug/kg (0.6mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
bird - domestic LDLo subcutaneous 100ug/kg (0.1mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1340, 1935.
bird - wild LDLo oral 7500ug/kg (7.5mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
bird - wild LDLo subcutaneous 100ug/kg (0.1mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
cat LD50 intravenous 810ug/kg (0.81mg/kg)   National Technical Information Service. Vol. AD-A028-501,
cat LDLo subcutaneous 1100ug/kg (1.1mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1340, 1935.
dog LD50 intravenous 1340ug/kg (1.34mg/kg)   National Technical Information Service. Vol. AD-A028-501,
dog LDLo oral 4mg/kg (4mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1340, 1935.
dog LDLo subcutaneous 1700ug/kg (1.7mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1340, 1935.
domestic animals - goat/sheep LD50 intravenous 660ug/kg (0.66mg/kg)   National Technical Information Service. Vol. PB158-508,
duck LDLo oral 3280ug/kg (3.28mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
frog LDLo subcutaneous 60mg/kg (60mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1340, 1935.
guinea pig LD50 intravenous 1430ug/kg (1.43mg/kg)   National Technical Information Service. Vol. AD-A028-501,
guinea pig LDLo subcutaneous 100ug/kg (0.1mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1340, 1935.
human LCLo inhalation 120mg/m3/1H (120mg/m3)   Journal of Industrial Hygiene and Toxicology. Vol. 24, Pg. 255, 1942.
human LCLo inhalation 200mg/m3/10M (200mg/m3) BEHAVIORAL: GENERAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING
World Health Organization, Technical Report Series. Vol. -, Pg. 30, 1970.
human LDLo oral 570ug/kg (0.57mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 596, 1966.
human LDLo subcutaneous 1mg/kg (1mg/kg)   Science Journal. Vol. 3(4), Pg. 33, 1967.
mammal (species unspecified) LCLo inhalation 36ppm/2H (36ppm)   Tabulae Biologicae. Vol. 3, Pg. 231, 1933.
mammal (species unspecified) LCLo inhalation 200ppm/5M (200ppm)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 138, Pg. 65, 1928.
man LCLo inhalation 400mg/m3/2M (400mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 75, 1982.
man LDLo unreported 1471ug/kg (1.471mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TCLo inhalation 500mg/m3/3M-C (500mg/m3) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: COMA

SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
Human Toxicology. Vol. 3, Pg. 57, 1984.
man TDLo intravenous 55ug/kg (0.055mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION National Technical Information Service. Vol. PB158-508,
monkey LD50 intravenous 1300ug/kg (1.3mg/kg)   National Technical Information Service. Vol. AD-A028-501,
mouse LC50 inhalation 323ppm/5M (323ppm)   Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977.
mouse LD50 intramuscular 2700ug/kg (2.7mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 23, Pg. 455, 1964.
mouse LD50 intraperitoneal 2990ug/kg (2.99mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 23, Pg. 455, 1964.
mouse LD50 intravenous 990ug/kg (0.99mg/kg)   National Technical Information Service. Vol. AD-A028-501,
mouse LD50 oral 3700ug/kg (3.7mg/kg)   Annales Pharmaceutiques Francaises. Vol. 19, Pg. 740, 1961.
mouse LDLo subcutaneous 3mg/kg (3mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1340, 1935.
pig LDLo oral 2mg/kg (2mg/kg)   Archives of Environmental Health. Vol. 22, Pg. 496, 1971.
pigeon LDLo intramuscular 1500ug/kg (1.5mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
pigeon LDLo oral 14mg/kg (14mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
pigeon LDLo subcutaneous 2150ug/kg (2.15mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
rabbit LC50 inhalation 208mg/m3/35M (208mg/m3) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES

CARDIAC: OTHER CHANGES

BLOOD: OTHER CHANGES
Toxic Substances Journal. Vol. 13, Pg. 263, 1994.
rabbit LD50 intramuscular 486ug/kg (0.486mg/kg)   Journal of the American College of Toxicology. Vol. 1(3), Pg. 120, 1982.
rabbit LD50 intraperitoneal 1570ug/kg (1.57mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 23, Pg. 455, 1964.
rabbit LD50 intravenous 660ug/kg (0.66mg/kg)   National Technical Information Service. Vol. AD-A028-501,
rabbit LD50 ocular 1040ug/kg (1.04mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: ATAXIA

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 2, Pg. 119, 1983.
rabbit LD50 subcutaneous 2500ug/kg (2.5mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 23, Pg. 455, 1964.
rabbit LDLo oral 4mg/kg (4mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1340, 1935.
rat LC50 inhalation 160ppm/30M (160ppm)   Fundamental and Applied Toxicology. Vol. 9, Pg. 236, 1987.
rat LD50 intravenous 810ug/kg (0.81mg/kg)   National Technical Information Service. Vol. AD-A028-501,

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -1.34E+01 deg C   EXP
Boiling Point 26 deg C   EXP
log P (octanol-water) -0.25 (none)   EXP
Water Solubility 1.00E+06 mg/L 25 EXP
Vapor Pressure 742 mm Hg 25 EXP
Henry's Law Constant 1.33E-04 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 3.00E-14 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.