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Substance Name: Amoxicillin mixture with Clavulanate potassium
RN: 74469-00-4
InChIKey: DWHGNUUWCJZQHO-ZVDZYBSKSA-M
Note
- A fixed-ratio combination of amoxicillin trihydrate and potassium clavulanate.
Molecular Formula
- C16-H19-N3-O5-S.C8-H9-N-O5.K
Molecular Weight
- 602.6593
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- beta-Lactamase Inhibitors
- Drug / Therapeutic Agent
- Enzyme Inhibitors
- Human Data
- Reproductive Effect
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Names and Synonyms
Results Name
- Amoxicillin mixture with Clavulanate potassium
Name of Substance
- Amoxicillin-potassium clavulanate combination
MeSH Heading
- Amoxicillin-potassium clavulanate combination
Synonyms
- Amocla
- Amoclan
- Amoclav
- Amoxicillin / clavulanic acid
- Amoxicillin and clavulanate potassium
- Amoxicillin clavulanate potassium
- Amoxicillin mixed with potassium clavulanate (2:1)
- Amoxicillin mixture with Clavulanate potassium
- Amoxsiklav
- Ancla
- Augmentan
- Augmentin
- Augmentin '125'
- Augmentin '200'
- Augmentin '250'
- Augmentin '400'
- Augmentin '500'
- Augmentin '875'
- Augmentin (antibiotic)
- Augmentin ES-600
- Augmentin XR
- Augmentine
- Auspilic
- BRL 25000
- BRL 25000A
- BRL 25000G
- Clamentin
- Clamobit
- Clavam
- Clavam 625
- Clavamox
- Clavinex
- Clavoxilin Plus
- Clavulin
- Clavumox
- Co-Amoxiclav
- Curam
- Eumetinex
- Kmoxilin
- Potassium clavulanate mixed with amoxicillin (1:2)
- Spectramox
- Viaclav
- Xiclav
Systematic Names
- 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R,3Z,5R)-, mixt. with (2S,5R,6R)-6-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
- 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, monopotassium salt, (2R-(2-alpha,3Z,5-alpha))-, mixt. with (2S-(2-alpha,5-alpha,6-beta(S*)))-6-((amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid (1:2)
Registry Numbers
CAS Registry Number
- 74469-00-4
Other Registry Number
- 74428-36-7
Related Registry Number
- 79198-29-1 (parent)
System Generated Number
- 0074469004
Molecular Formulas
Molecular Formula
- C16-H19-N3-O5-S.C8-H9-N-O5.K
Molecular Formula Fragments
- C16-H19-N3-O5-S
- C8-H9-N-O5
- COMPONENT
- K
Structure Descriptors
InChI
InChI=1S/C16H19N3O5S.C8H9NO5.K/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);1,6-7,10H,2-3H2,(H,12,13);/q;;+1/p-1/b;4-1-;/t9-,10-,11+,14-;6-,7-;/m11./s1InChIKey
DWHGNUUWCJZQHO-ZVDZYBSKSA-MSmiles
[K+].CC1(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
man | TDLo | oral | 600mg/kg/28D- (600mg/kg) | KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION BLOOD: EOSINOPHILIA LIVER: "JAUNDICE, CHOLESTATIC" | Acta Clinica Belgica. Vol. 46, Pg. 327, 1991. |
mouse | LD50 | intraperitoneal | 3925mg/kg (3925mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Chemotherapy Vol. 31(Suppl, |
mouse | LD50 | oral | > 15gm/kg (15000mg/kg) | Chemotherapy Vol. 31(Suppl, | |
mouse | LD50 | subcutaneous | 6433mg/kg (6433mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Chemotherapy Vol. 31(Suppl, |
rat | LD50 | intraperitoneal | 2774mg/kg (2774mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Chemotherapy Vol. 31(Suppl, |
rat | LD50 | oral | > 15gm/kg (15000mg/kg) | Chemotherapy Vol. 31(Suppl, | |
rat | LD50 | subcutaneous | 3487mg/kg (3487mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Chemotherapy Vol. 31(Suppl, |