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Substance Name: Potassium chloride [USP:JAN]
RN: 7447-40-7
UNII: 660YQ98I10
InChIKey: WCUXLLCKKVVCTQ-UHFFFAOYSA-M

Note

  • A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.

Molecular Formulas

  • Cl-K
  • K-Cl

Molecular Weight

  • 74.551
 

Classification Codes

  • Human Data
  • Mutation Data
  • Replenisher (Electrolyte)
  • Skin / Eye Irritant

Names and Synonyms

Name of Substance

  • Potassium chloride
  • Potassium chloride [USP:JAN]

MeSH Heading

  • Potassium chloride

Synonyms

  • Acronitol
  • Addi-K
  • Apo-K
  • Caswell No. 686
  • CCRIS 1962
  • Celeka
  • Cena-K
  • Chlorid draselny
  • Chlorid draselny [Czech]
  • Chloride of potash
  • Chloropotassuril
  • Chlorvescent
  • Clor-K-Zaf
  • Diffu-K
  • Dipotassium dichloride
  • Durekal
  • Durules
  • Durules-K
  • EC 231-211-8
  • EINECS 231-211-8
  • Emplets potassium chloride
  • Enpott
  • Enseal
  • EPA Pesticide Chemical Code 013904
  • Epiklor
  • HSDB 1252
  • K Tab
  • K+10
  • K+8
  • K-10
  • K-Care
  • K-Contin
  • K-Dur
  • K-Grad
  • K-Lease
  • K-Lor
  • K-Lyte Cl
  • K-Lyte/Cl
  • K-Norm
  • K-Predne-Dome
  • K-Sol
  • K-SR
  • K-Tab
  • Kadalex
  • Kalcorid
  • Kaleorid
  • Kali Chloratum
  • Kali Chloridum
  • Kali muriaticum
  • Kaliduron
  • Kaliglutol
  • Kalilente
  • Kalinor-Retard P
  • Kalinorm
  • Kalinorm Depottab
  • Kaliolite
  • Kalipor
  • Kalipoz
  • Kalitabs
  • Kalitrans Retard
  • Kalium Duriles
  • Kalium Durules
  • Kalium Retard
  • Kalium S.R.
  • Kalium SR
  • Kalium-Durettes
  • Kalium-R
  • Kaochlor
  • Kaon Cl
  • Kaon Cl-10
  • Kaon-Cl
  • Kaon-Cl 10
  • Kaon-Cl TABS
  • Kato
  • Kay Ciel
  • Kay-Cee-L
  • Kay-Ciel
  • Kay-EM
  • Kayciel
  • KCl
  • KCL Retard
  • KCl-retard Zyma
  • Keylyte
  • Klor-Con
  • Klor-Con 10
  • Klor-Con M10
  • Klor-Con M15
  • Klor-Con M20
  • Klor-Lyte
  • Kloren
  • Klorvess
  • Klotrix
  • KSR
  • Lento-K
  • Lento-Kalium
  • Leo-K
  • Micro-K
  • Micro-K 10
  • Micro-K Extentcaps
  • Micro-K LS
  • Micro-Kalium Retard
  • Miopotasio
  • Monopotassium chloride
  • Muriate of potash
  • Natural sylvite
  • Neobakasal
  • NSC 77368
  • Nu-K
  • Peter-kal
  • Pfiklor
  • Plus Kalium Retard
  • Potasion
  • Potasol
  • Potassii Chloridum
  • Potassium chloride
  • Potassium chloride (K3Cl3)
  • Potassium chloride (KCl)
  • Potassium chloride 10meq in plastic container
  • Potassium chloride 20meq in plastic container
  • Potassium chloride 30meq in plastic container
  • Potassium chloride 40meq in plastic container
  • Potassium chloride in plastic container
  • Potassium Cl
  • Potassium monochloride
  • Potassium muriate
  • Potavescent
  • Rekawan
  • Rekawan Retard
  • Repone K
  • Rum-K
  • Slow-K
  • Slow-K tablets
  • Span-K
  • Steropotassium
  • Super K
  • Super K (salt)
  • Ten-K
  • Tripotassium trichloride
  • Ultra K Chlor
  • Ultra-K-Chlor
  • UNII-660YQ98I10

Systematic Names

  • Potassium chloride
  • Potassium chloride (KCl)

Superlist Names

  • Potassium chloride
  • Potassium chloride solution

Mixture Names

  • Colyte
  • Infalyte
  • K-Lyte/Cl
  • K-Predne-Dome
  • Kolyum

Registry Numbers

CAS Registry Number

  • 7447-40-7

FDA UNII

  • 660YQ98I10

Other Registry Numbers

  • 1037073-81-6
  • 12599-00-7
  • 126415-35-8
  • 2018280-06-1
  • 59217-68-4
  • 79103-76-7

System Generated Number

  • 0007447407

Structure Descriptors

InChI

1S/ClH.K/h1H;/q;+1/p-1

InChIKey

WCUXLLCKKVVCTQ-UHFFFAOYSA-M

Smiles

[Cl-].[K+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo subcutaneous 2120mg/kg (2120mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
guinea pig LDLo intraarterial 130mg/kg (130mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo intraperitoneal 900mg/kg (900mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 35, Pg. 1, 1929.
guinea pig LDLo intravenous 77mg/kg (77mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo oral 2500mg/kg (2500mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 35, Pg. 1, 1929.
guinea pig LDLo parenteral 40mg/kg (40mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo subcutaneous 2550mg/kg (2550mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
infant LDLo oral 938mg/kg/2D (938mg/kg)   JAMA, Journal of the American Medical Association. Vol. 240, Pg. 1339, 1978.
infant LDLo oral 938mg/kg/2D (938mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
JAMA, Journal of the American Medical Association. Vol. 240, Pg. 1339, 1978.
man LDLo oral 20mg/kg (20mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

BLOOD: CHANGE IN CLOTTING FACTORS
Lancet. Vol. 2, Pg. 919, 1980.
mouse LD50 intraperitoneal 620mg/kg (620mg/kg)   Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.
mouse LD50 intravenous 117mg/kg (117mg/kg)   European Journal of Toxicology and Environmental Hygiene. Vol. 8, Pg. 188, 1975.
mouse LD50 oral 1500mg/kg (1500mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 257, 1990.
pigeon LDLo subcutaneous 2210mg/kg (2210mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat LD50 intraperitoneal 660mg/kg (660mg/kg)   Food and Cosmetics Toxicology. Vol. 3, Pg. 597, 1965.
rat LD50 intravenous 142mg/kg (142mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 1128, 1964.
rat LD50 oral 2600mg/kg (2600mg/kg)   "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972Vol. -, Pg. 8, 1972.
women TDLo oral 60mg/kg/D (60mg/kg) BLOOD: CHANGE IN CLOTTING FACTORS

GASTROINTESTINAL: NAUSEA OR VOMITING
Lancet. Vol. 2, Pg. 919, 1980.