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Substance Name: Lithium chloride
RN: 7447-41-8
UNII: G4962QA067
InChIKey: KWGKDLIKAYFUFQ-UHFFFAOYSA-M

Note

  • A salt of lithium that has been used experimentally as an immunomodulator.

Molecular Formula

  • Cl-Li

Molecular Weight

  • 42.394
 

Classification Codes

  • Adjuvants, Immunologic
  • Antimanic Agents
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Drug / Therapeutic Agent
  • Human Data
  • Immunologic Factors
  • Mutation Data
  • Psychotropic Drugs
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tranquilizing Agents
  • Tumor Data
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Names and Synonyms

Name of Substance

  • Lithium chloride

MeSH Heading

  • Lithium chloride

Synonyms

  • CCRIS 5924
  • Chlorku litu
  • Chlorku litu [Polish]
  • Chlorure de lithium
  • Chlorure de lithium [French]
  • EC 231-212-3
  • EINECS 231-212-3
  • HSDB 4281
  • Lithium chloride
  • NSC 327172
  • UNII-G4962QA067

Systematic Names

  • Lithium chloride
  • Lithium chloride (LiCl)

Superlist Name

  • Luthium chloride

Registry Numbers

CAS Registry Number

  • 7447-41-8

FDA UNII

  • G4962QA067

Other Registry Numbers

  • 1220508-63-3
  • 1309791-76-1
  • 2018280-04-9
  • 404596-80-1

System Generated Number

  • 0007447418

Structure Descriptors

InChI

1S/ClH.Li/h1H;/q;+1/p-1

InChIKey

KWGKDLIKAYFUFQ-UHFFFAOYSA-M

Smiles

[Li]Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 422mg/kg (422mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat LD50 intraperitoneal 492mg/kg (492mg/kg)   Russian Pharmacology and Toxicology Vol. 42, Pg. 9, 1979.
cat LDLo subcutaneous 450mg/kg (450mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
dog LDLo intravenous 500mg/kg (500mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

MUSCULOSKELETAL: OTHER CHANGES

BEHAVIORAL: FOOD INTAKE (ANIMAL)
Journal of Pharmacology and Experimental Therapeutics. Vol. 100, Pg. 429, 1950.
frog LDLo subcutaneous 885mg/kg (885mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
guinea pig LD50 intraperitoneal 624mg/kg (624mg/kg)   "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 157, 1999.
guinea pig LDLo subcutaneous 620mg/kg (620mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
human LDLo oral 200mg/kg/3D (200mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: MUSCLE WEAKNESS
JAMA, Journal of the American Medical Association. Vol. 139, Pg. 688, 1949.
human TDLo oral 243mg/kg/13D (243mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: TREMOR
JAMA, Journal of the American Medical Association. Vol. 139, Pg. 688, 1949.
mouse LD50 intracrebral 14040ug/kg (14.04mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 75, 1973.
mouse LD50 intraperitoneal 600mg/kg (600mg/kg)   Journal of Thermal Biology. Vol. 6, Pg. 87, 1981.
mouse LD50 intravenous 363mg/kg (363mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS
Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 413, 1973.
mouse LD50 oral 1165mg/kg (1165mg/kg)   Russian Pharmacology and Toxicology Vol. 33, Pg. 266, 1970.
mouse LD50 subcutaneous 738mg/kg (738mg/kg) MUSCULOSKELETAL: OTHER CHANGES

BEHAVIORAL: TREMOR
Acta Pharmacologica et Toxicologica. Vol. 43, Pg. 51, 1978.
pigeon LDLo subcutaneous 513mg/kg (513mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
quail LD50 oral 422mg/kg (422mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
rabbit LD50 oral 800mg/kg (800mg/kg)   Farmakologiya i Toksikologiya Vol. 39, Pg. 53, 1976.
rabbit LDLo subcutaneous 531mg/kg (531mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 intracrebral 4800ug/kg (4.8mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 26, Pg. 399, 1974.
rat LD50 intracrebral 4800ug/kg (4.8mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Polish Journal of Pharmacology and Pharmacy. Vol. 26, Pg. 399, 1974.
rat LD50 intraperitoneal 514mg/kg (514mg/kg)   Personal Communication from K.P. Petersen, DAK Labs., 59 Lergravsvej, DK-2300, Copenhagen, Demark, Dec. 22, 1977Vol. 22DEC1977,
rat LD50 intratracheal 205mg/kg (205mg/kg)   "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 157, 1999.
rat LD50 oral 526mg/kg (526mg/kg)   Acta Pharmacologica et Toxicologica. Vol. 47, Pg. 351, 1980.
rat LD50 subcutaneous 499mg/kg (499mg/kg)   Personal Communication from K.P. Petersen, DAK Labs., 59 Lergravsvej, DK-2300, Copenhagen, Demark, Dec. 22, 1977Vol. 22DEC1977,