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Substance Name: Tylosin tartrate
RN: 74610-55-2
UNII: 5P4625C51T
InChIKey: ICVKYYINQHWDLM-KBEWXLTPSA-N

Molecular Formula

  • C46-H77-N-O17.C4-H6-O6

Molecular Weight

  • 1066.1897
 
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Names and Synonyms

Name of Substance

  • Tylosin tartrate

Synonyms

  • EINECS 215-781-5
  • Pharmasin
  • Tylan injectable
  • Tylan soluble
  • Tylosin tartrate
  • Tylosin tartrate [GREEN BOOK]
  • Tylosin tartrate [MART.]
  • Tylosin tartrate [USP]
  • Tylosin tartrate [WHO-DD]
  • Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
  • UNII-5P4625C51T

Registry Numbers

CAS Registry Number

  • 74610-55-2

FDA UNII

  • 5P4625C51T

Other Registry Numbers

  • 1405-54-5
  • 61913-18-6
  • 65608-64-2
  • 8075-70-5

System Generated Number

  • 0074610552

Structure Descriptors

InChI

1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1

InChIKey

ICVKYYINQHWDLM-KBEWXLTPSA-N

Smiles

CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 intramuscular 432mg/kg (432mg/kg)   Antimicrobial Agents Annual. Vol. -, Pg. 595, 1960.
chicken LD50 intravenous 48mg/kg (48mg/kg) BEHAVIORAL: IRRITABILITY

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Veterinarno-Meditsinski Nauki. Veterinary Science. Vol. 15, Pg. 52, 1978.
chicken LD50 oral 5400mg/kg (5400mg/kg)   Antimicrobial Agents Annual. Vol. -, Pg. 595, 1960.
chicken LD50 subcutaneous 620mg/kg (620mg/kg) BEHAVIORAL: IRRITABILITY

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Veterinarno-Meditsinski Nauki. Veterinary Science. Vol. 15, Pg. 52, 1978.
guinea pig LD50 oral > 1gm/kg (1000mg/kg)   Antimicrobial Agents Annual. Vol. -, Pg. 595, 1960.
mouse LD50 intravenous 589mg/kg (589mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Food and Cosmetics Toxicology. Vol. 4, Pg. 1, 1966.
mouse LD50 oral > 6200mg/kg (6200mg/kg)   Antimicrobial Agents Annual. Vol. -, Pg. 595, 1960.
mouse LD50 subcutaneous 1354mg/kg (1354mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Food and Cosmetics Toxicology. Vol. 4, Pg. 1, 1966.
rat LD50 intravenous 695mg/kg (695mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Food and Cosmetics Toxicology. Vol. 4, Pg. 1, 1966.
rat LD50 oral > 6200mg/kg (6200mg/kg)   Antimicrobial Agents Annual. Vol. -, Pg. 595, 1960.