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Substance Name: Docarpamine [INN]
RN: 74639-40-0
UNII: RPQ57D8S72
InChIKey: ZLVMAMIPILWYHQ-INIZCTEOSA-N
Note
- A dopamine prodrug.
Molecular Formula
- C21-H30-N2-O8-S
Molecular Weight
- 470.54
Classification Codes
- Dopamine Agents
- Dopamine Agonists
- Drug / Therapeutic Agent
- Neurotransmitter Agents
- Reproductive Effect
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Names and Synonyms
Name of Substance
- Docarpamine
- Docarpamine [INN]
Synonyms
- Docarpamina
- Docarpamina [INN-Spanish]
- Docarpamine
- Docarpaminum
- Docarpaminum [INN-Latin]
- N-(N-Acetyl-L-methionyl)-O,O-bis(ethoxycarbonyl)dopamine
- TA-870
- UNII-RPQ57D8S72
Systematic Names
- (-)-(S)-2-Acetamido-N-(3,4-dihydroxyphenethyl)-4-(methylthio)butyramide bis(ethyl carbonate) (ester)
- Carbonic acid, 4-(2-((2-(acetylamino)-4-(methylthio)-1-oxobutyl)amino)ethyl)-1,2-phenylene diethyl ester, (S)-
Registry Numbers
CAS Registry Number
- 74639-40-0
FDA UNII
- RPQ57D8S72
System Generated Number
- 0074639400
Structure Descriptors
InChI
InChI=1S/C21H30N2O8S/c1-5-28-20(26)30-17-8-7-15(13-18(17)31-21(27)29-6-2)9-11-22-19(25)16(10-12-32-4)23-14(3)24/h7-8,13,16H,5-6,9-12H2,1-4H3,(H,22,25)(H,23,24)/t16-/m0/s1InChIKey
ZLVMAMIPILWYHQ-INIZCTEOSA-NSmiles
CCOC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | oral | 2gm/kg (2000mg/kg) | Cardiovascular Drug Reviews. Vol. 10, Pg. 101, 1992. | |
dog | LD50 | subcutaneous | > 2gm/kg (2000mg/kg) | Drugs in Japan Vol. -, Pg. 836, 1995. | |
rat | LD50 | oral | 2gm/kg (2000mg/kg) | Cardiovascular Drug Reviews. Vol. 10, Pg. 101, 1992. | |
rat | LD50 | subcutaneous | 1gm/kg (1000mg/kg) | Cardiovascular Drug Reviews. Vol. 10, Pg. 101, 1992. |