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Substance Name: Mercuric chloride [JAN:ISO]
RN: 7487-94-7
UNII: 53GH7MZT1R
InChIKey: LWJROJCJINYWOX-UHFFFAOYSA-L

Note

  • Mercury chloride (HgCl2). A highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a topical antiseptic and disinfectant.

Molecular Formulas

  • Cl2-Hg
  • Hg-Cl2

Molecular Weight

  • 271.496
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Anti-Infective Agents
  • Anti-Infective Agents, Local
  • Disinfectants
  • Drug / Therapeutic Agent
  • Fungicide, Bactericide, Wood Preservative
  • Human Data
  • Insecticide
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 241
  • 2011 CERCLA Priority List, Rank: 234
  • Overall Carcinogenic Evaluation: Group 3
  • Threshold Planning Quantity (TPQ) = 500/10000 lb

Names and Synonyms

Results Name

  • Mercuric chloride [JAN:ISO]

Name of Substance

  • Mercuric chloride
  • Mercuric chloride [JAN]

MeSH Heading

  • Mercuric chloride

Synonyms

  • Abavit B
  • Bichloride of mercury
  • Bichlorure de mercure
  • Bichlorure de mercure [French]
  • Calo-Clor
  • Calochlor
  • Calocure
  • Caswell No. 544
  • CCRIS 4838
  • Chlorid rtutnaty
  • Chlorid rtutnaty [Czech]
  • Chlorure mercurique
  • Chlorure mercurique [French]
  • Chlorure mercurique [ISO-French]
  • Cloruro di mercurio
  • Cloruro di mercurio [Italian]
  • Corrosive mercury chloride
  • Corrosive sublimate
  • Dichloromercury
  • EINECS 231-299-8
  • EPA Pesticide Chemical Code 052001
  • Fungchex
  • HSDB 33
  • Hydraargyrum bichloratum
  • Mercuric bichloride
  • Mercuric chloride
  • Mercuric chloride [ISO]
  • Mercury bichloride
  • Mercury chloride (HgCl2)
  • Mercury dichloride
  • Mercury perchloride
  • Mercury(2+) chloride
  • Mercury(II) chloride
  • NCI-C60173
  • NSC 353255
  • Perchloride of mercury
  • Quecksilber chlorid
  • Quecksilber chlorid [German]
  • Sublimat
  • Sublimat [Czech]
  • Sublimate
  • Sulem
  • Sulema
  • Sulema [Russian]
  • TL 898
  • UNII-53GH7MZT1R

Systematic Names

  • Mercuric chloride
  • Mercury chloride (HgCl2)
  • Mercury dichloride
  • Mercury(II) chloride

Superlist Names

  • Mercuric chloride
  • Mercuric chloride [Mercury and mercury compounds]
  • Mercuric chloride [UN1624] [Poison]
  • Mercury bichloride
  • UN1624

Registry Numbers

CAS Registry Number

  • 7487-94-7

FDA UNII

  • 53GH7MZT1R

System Generated Number

  • 0007487947

Structure Descriptors

InChI

1S/2ClH.Hg/h2*1H;/q;;+2/p-2

InChIKey

LWJROJCJINYWOX-UHFFFAOYSA-L

Smiles

[Hg](Cl)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 2710ug/kg (2.71mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 44, Pg. 423, 1932.
dog LDLo oral 10mg/kg (10mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
frog LD50 intramuscular 7579ug/kg (7.579mg/kg)   Comparative Biochemistry and Physiology, C: Pharmacology, Toxicology and Endocrinology. Vol. 85, Pg. 253, 1986.
frog LD50 intramuscular 7579ug/kg (7.579mg/kg)   Comparative Biochemistry and Physiology, C: Pharmacology, Toxicology and Endocrinology. Vol. 85, Pg. 253, 1986.
frog LD50 intramuscular 7579ug/kg (7.579mg/kg)   Comparative Biochemistry and Physiology, C: Pharmacology, Toxicology and Endocrinology. Vol. 85, Pg. 253, 1986.
frog LDLo oral 2424mg/kg (2424mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
frog LDLo subcutaneous 2gm/kg (2000mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
guinea pig LDLo intraperitoneal 345mg/kg (345mg/kg)   Archives of Environmental Health. Vol. 11, Pg. 201, 1965.
guinea pig LDLo skin 345mg/kg (345mg/kg)   Archives of Environmental Health. Vol. 11, Pg. 201, 1965.
human LDLo oral 29mg/kg (29mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE

GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM DUODENUM
New England Journal of Medicine. Vol. 244, Pg. 459, 1951.
man LDLo oral 14286ug/kg (14.286mg/kg) KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 41, Pg. 2383, 1999.
man LDLo oral 86mg/kg (86mg/kg) VASCULAR: CHANGE IN PLASMA OR BLOOD VALUME

GASTROINTESTINAL: NECROTIC GHANGES

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
Journal of Toxicology, Clinical Toxicology. Vol. 26, Pg. 189, 1988.
man LDLo oral 143mg/kg (143mg/kg) BLOOD: CHANGES IN LEUCOCYTE (WBC) COUNT

BEHAVIORAL: EXCITEMENT

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Igaku to Seibutsugaku. Medicine and Biology. Vol. 2, Pg. 48, 1942.
man LDLo unreported 7253ug/kg (7.253mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TDLo oral 21mg/kg (21mg/kg) GASTROINTESTINAL: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION

KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS
Clinical Toxicology. Vol. 11, Pg. 309, 1977.
man TDLo oral 29mg/kg (29mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION

KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED
Medical Journal of Australia. Vol. 2, Pg. 125, 1978.
man TDLo oral 57mg/kg (57mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

LIVER: LIVER FUNCTION TESTS IMPAIRED

GASTROINTESTINAL: GASTRITIS
Japanese Journal of Toxicology. Vol. 8, Pg. 157, 1995.
mouse LCLo inhalation 300mg/m3/10M (300mg/m3)   National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. No.9-4-1-9, Pg. 1943,
mouse LD50 intraperitoneal 3900ug/kg (3.9mg/kg)   Pharmaceutical Chemistry Journal Vol. 25, Pg. 891, 1991.
mouse LD50 intravenous 4992ug/kg (4.992mg/kg)   Quarterly Journal of Pharmacy & Pharmacology. Vol. 21, Pg. 364, 1948.
mouse LD50 oral 6mg/kg (6mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(1), Pg. 76, 1986.
mouse LD50 subcutaneous 4500ug/kg (4.5mg/kg)   Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. Vol. 34, Pg. 193, 1979.
pigeon LDLo oral 2200mg/kg (2200mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1389, 1935.
pigeon LDLo subcutaneous 1100mg/kg (1100mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1389, 1935.
quail LD50 intramuscular 34mg/kg (34mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA
Journal of Toxicology and Environmental Health. Vol. 20, Pg. 105, 1987.
quail LD50 oral 36mg/kg (36mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA
Journal of Toxicology and Environmental Health. Vol. 20, Pg. 105, 1987.
rabbit LD50 intramuscular 7300ug/kg (7.3mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 87, Pg. 119, 1946.
rabbit LDLo intravenous 2mg/kg (2mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Pharmacology and Experimental Therapeutics. Vol. 35, Pg. 343, 1929.
rabbit LDLo oral 20mg/kg (20mg/kg)   "Ueber die Wirkung Verschiedener Gifte Auf Vogel, Dissertation," Forchheimer, L., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
rabbit LDLo subcutaneous 10mg/kg (10mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 intraperitoneal 3210ug/kg (3.21mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Proceedings of the European Society for the Study of Drug Toxicity. Vol. 12, Pg. 247, 1971.
rat LD50 intravenous 1272ug/kg (1.272mg/kg)   Archives of Toxicology. Vol. 58, Pg. 243, 1986.
rat LD50 oral 1mg/kg (1mg/kg)   Pesticide Manual. Vol. 9, Pg. 550, 1991.
rat LD50 skin 41mg/kg (41mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(7), Pg. 27, 1981.
rat LD50 subcutaneous 14mg/kg (14mg/kg)   Japanese Journal of Experimental Medicine. Vol. 39, Pg. 47, 1969.
women TDLo oral 18mg/kg (18mg/kg) BLOOD: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED
Human & Experimental Toxicology. Vol. 11, Pg. 53, 1992.
women TDLo oral 50mg/kg (50mg/kg) KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED

GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: OTHER CHANGES
American Journal of Obstetrics and Gynecology. Vol. 80, Pg. 145, 1960.