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Substance Name: Piracetam [USAN:INN:BAN]
RN: 7491-74-9
UNII: ZH516LNZ10
InChIKey: GMZVRMREEHBGGF-UHFFFAOYSA-N
Note
- A compound suggested to be both a nootropic and a neuroprotective agent.
Molecular Formula
- C6-H10-N2-O2
Molecular Weight
- 142.157
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Central Nervous System Agents
- Cognition Adjuvant
- Drug / Therapeutic Agent
- Neuroprotective Agents
- Nootropic Agents
- Protective Agents
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Names and Synonyms
Name of Substance
- Piracetam
- Piracetam [USAN:INN:BAN]
MeSH Heading
- Piracetam
Synonyms
- 1-Acetamido-2-pyrrolidinone
- 2-Ketopyrrolidine-1-ylacetamide
- 2-Oxo-1-pyrrolidineacetamide
- 2-Oxo-pyrrolidin-1-ylacetamide
- 2-Oxo-pyrrolidine acetamide
- 2-Pyrrolidinoneacetamide
- 2-Pyrrolidoneacetamide
- 5-21-06-00360 (Beilstein Handbook Reference)
- Breinox
- BRN 1526393
- Ciclofalina
- Cl-871
- EINECS 231-312-7
- Euvifor
- Gabacet
- Genogris
- HSDB 7529
- KT-801
- Naofukang
- Naofukang [Chinese]
- Nootron
- Nootropil
- Nootropyl
- Normabrain
- Piracetam
- Piracetamum
- Piracetamum [INN-Latin]
- Pirroxil
- Pyracetam
- Pyramem
- UCB 6215
- UNII-ZH516LNZ10
Systematic Names
- 1-Pyrrolidineacetamide, 2-oxo-
- Piracetam
Registry Numbers
CAS Registry Number
- 7491-74-9
FDA UNII
- ZH516LNZ10
System Generated Number
- 0007491749
Structure Descriptors
InChI
InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)InChIKey
GMZVRMREEHBGGF-UHFFFAOYSA-NSmiles
NC(=O)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cat | LD50 | intravenous | 10gm/kg (10000mg/kg) | Russian Pharmacology and Toxicology Vol. 47, Pg. 205, 1984. | |
| mammal (species unspecified) | LD50 | unreported | > 10gm/kg (10000mg/kg) | Russian Pharmacology and Toxicology Vol. 44, Pg. 22, 1981. | |
| mouse | LD50 | intraperitoneal | > 10gm/kg (10000mg/kg) | Pharmaceutical Chemistry Journal Vol. 23, Pg. 795, 1989. | |
| mouse | LD50 | intravenous | 9200mg/kg (9200mg/kg) | Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 18, Pg. 465, 1983. | |
| mouse | LD50 | oral | 2gm/kg (2000mg/kg) | Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 24(4), Pg. 32, 1990. | |
| mouse | LD50 | subcutaneous | > 12gm/kg (12000mg/kg) | Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 11(8), Pg. 132, 1977. | |
| rat | LDLo | oral | 5600mg/kg (5600mg/kg) | Farmaco, Edizione Pratica. Vol. 32, Pg. 47, 1977. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| log P (octanol-water) | -1.54E+00 | (none) | EXP | |
| Water Solubility | 8.30E+04 | mg/L | 25 | EST |
| Vapor Pressure | 1.08E-05 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.52E-10 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 2.63E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.