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Substance Name: Piracetam [USAN:INN:BAN]
RN: 7491-74-9
UNII: ZH516LNZ10
InChIKey: GMZVRMREEHBGGF-UHFFFAOYSA-N

Note

  • A compound suggested to be both a nootropic and a neuroprotective agent.

Molecular Formula

  • C6-H10-N2-O2

Molecular Weight

  • 142.157
 

Classification Codes

  • Central Nervous System Agents
  • Cognition Adjuvant
  • Drug / Therapeutic Agent
  • Neuroprotective Agents
  • Nootropic Agents
  • Protective Agents

Names and Synonyms

Name of Substance

  • Piracetam
  • Piracetam [USAN:INN:BAN]

MeSH Heading

  • Piracetam

Synonyms

  • 1-Acetamido-2-pyrrolidinone
  • 2-Ketopyrrolidine-1-ylacetamide
  • 2-Oxo-1-pyrrolidineacetamide
  • 2-Oxo-pyrrolidin-1-ylacetamide
  • 2-Oxo-pyrrolidine acetamide
  • 2-Pyrrolidinoneacetamide
  • 2-Pyrrolidoneacetamide
  • 5-21-06-00360 (Beilstein Handbook Reference)
  • Breinox
  • BRN 1526393
  • Ciclofalina
  • Cl-871
  • EINECS 231-312-7
  • Euvifor
  • Gabacet
  • Genogris
  • HSDB 7529
  • KT-801
  • Naofukang
  • Naofukang [Chinese]
  • Nootron
  • Nootropil
  • Nootropyl
  • Normabrain
  • Piracetam
  • Piracetamum
  • Piracetamum [INN-Latin]
  • Pirroxil
  • Pyracetam
  • Pyramem
  • UCB 6215
  • UNII-ZH516LNZ10

Systematic Names

  • 1-Pyrrolidineacetamide, 2-oxo-
  • Piracetam

Registry Numbers

CAS Registry Number

  • 7491-74-9

FDA UNII

  • ZH516LNZ10

System Generated Number

  • 0007491749

Structure Descriptors

InChI

InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)

InChIKey

GMZVRMREEHBGGF-UHFFFAOYSA-N

Smiles

NC(=O)CN1CCCC1=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intravenous 10gm/kg (10000mg/kg)   Russian Pharmacology and Toxicology Vol. 47, Pg. 205, 1984.
mammal (species unspecified) LD50 unreported > 10gm/kg (10000mg/kg)   Russian Pharmacology and Toxicology Vol. 44, Pg. 22, 1981.
mouse LD50 intraperitoneal > 10gm/kg (10000mg/kg)   Pharmaceutical Chemistry Journal Vol. 23, Pg. 795, 1989.
mouse LD50 intravenous 9200mg/kg (9200mg/kg)   Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 18, Pg. 465, 1983.
mouse LD50 oral 2gm/kg (2000mg/kg)   Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 24(4), Pg. 32, 1990.
mouse LD50 subcutaneous > 12gm/kg (12000mg/kg)   Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 11(8), Pg. 132, 1977.
rat LDLo oral 5600mg/kg (5600mg/kg)   Farmaco, Edizione Pratica. Vol. 32, Pg. 47, 1977.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) -1.54E+00 (none)   EXP
Water Solubility 8.30E+04 mg/L 25 EST
Vapor Pressure 1.08E-05 mm Hg 25 EST
Henry's Law Constant 1.52E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.63E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.