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Substance Name: Barbatolysin
RN: 74967-92-3

Note

  • A cytolytic peptide isolated from the venom of the red harvester ant, Pogonomyrmex barbatus.
 

Classification Code

  • Natural Product
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Names and Synonyms

Name of Substance

  • Barbatolysin

Synonyms

  • Barbatolysin
  • P. barbatus venom
  • Pogonomyrmex barbatus venom

Systematic Name

  • Venom, ant, Pogonomyrmex barbatus

Registry Numbers

CAS Registry Number

  • 74967-92-3

System Generated Number

  • 0074967923

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intraperitoneal 2950ug/kg (2.95mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Toxicology and Applied Pharmacology. Vol. 10, Pg. 394, 1967.
mouse LD50 intraperitoneal 620ug/kg (0.62mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Toxicon. Vol. 18, Pg. 469, 1980.
mouse LD50 subcutaneous 45mg/kg (45mg/kg)   Toxicology and Applied Pharmacology. Vol. 10, Pg. 394, 1967.