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Substance Name: Acetaldehyde
RN: 75-07-0
UNII: GO1N1ZPR3B
InChIKey: IKHGUXGNUITLKF-UHFFFAOYSA-N
Note
- A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
Molecular Formula
- C2-H4-O
Molecular Weight
- 44.0526
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Human Data
- Mutation Data
- Reproductive Effect
- Skin / Eye Irritant
- Tumor Data
Superlist Classification Codes
- Ceiling (25 ppm); Confirmed animal carcinogen with unknown relevance to humans
- Overall Carcinogenic Evaluation: Group 2B
- Reasonably Anticipated to be a Carcinogen
- Reportable Quantity (RQ) = 1000 lb
- TWA 200 ppm (360 mg/m3)
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Names and Synonyms
Name of Substance
- Acetaldehyde
MeSH Heading
- Acetaldehyde
Synonyms
- Acetaldehyd
- Acetaldehyd [German]
- Acetaldehyde
- Acetaldehyde (natural)
- Acetic aldehyde
- Acetic ethanol
- Acetylaldehyde
- AI3-31167
- Aldehyde acetique
- Aldehyde acetique [French]
- Aldeide acetica
- Aldeide acetica [Italian]
- CCRIS 1396
- EC 200-836-8
- EINECS 200-836-8
- Ethanal
- Ethyl aldehyde
- FEMA No. 2003
- HSDB 230
- NCI-C56326
- NSC 7594
- Octowy aldehyd
- Octowy aldehyd [Polish]
- RCRA waste number U001
- UNII-GO1N1ZPR3B
Systematic Name
- Acetaldehyde
Superlist Names
- Acetaldehyde
- Acetaldehyde [UN1089] [Flammable liquid]
- Ethanal
- RCRA waste no. U001
- UN1089
Registry Numbers
CAS Registry Number
- 75-07-0
FDA UNII
- GO1N1ZPR3B
System Generated Number
- 0000075070
Structure Descriptors
InChI
InChI=1S/C2H4O/c1-2-3/h2H,1H3InChIKey
IKHGUXGNUITLKF-UHFFFAOYSA-NSmiles
CC=OToxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
frog | LDLo | intravenous | 800mg/kg (800mg/kg) | CARDIAC: OTHER CHANGES BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927. |
hamster | LC50 | inhalation | 17000ppm/4H (17000ppm) | Progress in Experimental Tumor Research. Vol. 24, Pg. 162, 1979. | |
hamster | LD50 | intratracheal | 96mg/kg (96mg/kg) | Progress in Experimental Tumor Research. Vol. 24, Pg. 162, 1979. | |
human | TCLo | inhalation | 134ppm/30M (134ppm) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | JAMA, Journal of the American Medical Association. Vol. 165, Pg. 1908, 1957. |
mammal (species unspecified) | LC50 | inhalation | 20100mg/m3 (20100mg/m3) | BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(7), Pg. 54, 1975. |
mouse | LC50 | inhalation | 23gm/m3/4H (23000mg/m3) | Current Toxicology. Vol. 1, Pg. 47, 1993. | |
mouse | LD50 | intraperitoneal | 500mg/kg (500mg/kg) | IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 36, Pg. 101, 1985. | |
mouse | LD50 | oral | 900mg/kg (900mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(11), Pg. 57, 1981. | |
mouse | LD50 | subcutaneous | 560mg/kg (560mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC | Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950. |
rabbit | LD50 | skin | 3540mg/kg (3540mg/kg) | Union Carbide Data Sheet. Vol. 12/13/1963, | |
rabbit | LDLo | intravenous | 300mg/kg (300mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927. |
rabbit | LDLo | subcutaneous | 1200mg/kg (1200mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927. |
rat | LC50 | inhalation | 13300ppm/4H (13300ppm) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: EXCITEMENT | National Technical Information Service. Vol. OTS0534485, |
rat | LD50 | oral | 661mg/kg (661mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Agents and Actions, A Swiss Journal of Pharmacology. Vol. 4, Pg. 125, 1974. |
rat | LD50 | subcutaneous | 640mg/kg (640mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC | Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950. |
rat | LDLo | intraperitoneal | 500mg/kg (500mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Biological Chemistry. Vol. 152, Pg. 41, 1944. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | -1.23E+02 | deg C | EXP | |
Boiling Point | 20.1 | deg C | EXP | |
pKa Dissociation Constant | 13.57 | (none) | 25 | EXP |
log P (octanol-water) | -0.34 | (none) | EXP | |
Water Solubility | 1.00E+06 | mg/L | 25 | EXP |
Vapor Pressure | 902 | mm Hg | 25 | EXP |
Henry's Law Constant | 6.67E-05 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 1.58E-11 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.