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Substance Name: Acetaldehyde
RN: 75-07-0
UNII: GO1N1ZPR3B
InChIKey: IKHGUXGNUITLKF-UHFFFAOYSA-N

Note

  • A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.

Molecular Formula

  • C2-H4-O

Molecular Weight

  • 44.0526
 

Classification Codes

Classification Codes

  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • Ceiling (25 ppm); Confirmed animal carcinogen with unknown relevance to humans
  • Overall Carcinogenic Evaluation: Group 2B
  • Reasonably Anticipated to be a Carcinogen
  • Reportable Quantity (RQ) = 1000 lb
  • TWA 200 ppm (360 mg/m3)

Names and Synonyms

Name of Substance

  • Acetaldehyde

MeSH Heading

  • Acetaldehyde

Synonyms

  • Acetaldehyd
  • Acetaldehyd [German]
  • Acetaldehyde
  • Acetaldehyde (natural)
  • Acetic aldehyde
  • Acetic ethanol
  • Acetylaldehyde
  • AI3-31167
  • Aldehyde acetique
  • Aldehyde acetique [French]
  • Aldeide acetica
  • Aldeide acetica [Italian]
  • CCRIS 1396
  • EC 200-836-8
  • EINECS 200-836-8
  • Ethanal
  • Ethyl aldehyde
  • FEMA No. 2003
  • HSDB 230
  • NCI-C56326
  • NSC 7594
  • Octowy aldehyd
  • Octowy aldehyd [Polish]
  • RCRA waste number U001
  • UNII-GO1N1ZPR3B

Systematic Name

  • Acetaldehyde

Superlist Names

  • Acetaldehyde
  • Acetaldehyde [UN1089] [Flammable liquid]
  • Ethanal
  • RCRA waste no. U001
  • UN1089

Registry Numbers

CAS Registry Number

  • 75-07-0

FDA UNII

  • GO1N1ZPR3B

System Generated Number

  • 0000075070

Structure Descriptors

InChI

InChI=1S/C2H4O/c1-2-3/h2H,1H3

InChIKey

IKHGUXGNUITLKF-UHFFFAOYSA-N

Smiles

CC=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo intravenous 800mg/kg (800mg/kg) CARDIAC: OTHER CHANGES

BEHAVIORAL: GENERAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
hamster LC50 inhalation 17000ppm/4H (17000ppm)   Progress in Experimental Tumor Research. Vol. 24, Pg. 162, 1979.
hamster LD50 intratracheal 96mg/kg (96mg/kg)   Progress in Experimental Tumor Research. Vol. 24, Pg. 162, 1979.
human TCLo inhalation 134ppm/30M (134ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES JAMA, Journal of the American Medical Association. Vol. 165, Pg. 1908, 1957.
mammal (species unspecified) LC50 inhalation 20100mg/m3 (20100mg/m3) BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE		 Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(7), Pg. 54, 1975.
mouse LC50 inhalation 23gm/m3/4H (23000mg/m3)   Current Toxicology. Vol. 1, Pg. 47, 1993.
mouse LD50 intraperitoneal 500mg/kg (500mg/kg)   IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 36, Pg. 101, 1985.
mouse LD50 oral 900mg/kg (900mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(11), Pg. 57, 1981.
mouse LD50 subcutaneous 560mg/kg (560mg/kg) BEHAVIORAL: GENERAL ANESTHETIC Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
rabbit LD50 skin 3540mg/kg (3540mg/kg)   Union Carbide Data Sheet. Vol. 12/13/1963,
rabbit LDLo intravenous 300mg/kg (300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
rabbit LDLo subcutaneous 1200mg/kg (1200mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 429, 1927.
rat LC50 inhalation 13300ppm/4H (13300ppm) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: EXCITEMENT		 National Technical Information Service. Vol. OTS0534485,
rat LD50 oral 661mg/kg (661mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Agents and Actions, A Swiss Journal of Pharmacology. Vol. 4, Pg. 125, 1974.
rat LD50 subcutaneous 640mg/kg (640mg/kg) BEHAVIORAL: GENERAL ANESTHETIC Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
rat LDLo intraperitoneal 500mg/kg (500mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Journal of Biological Chemistry. Vol. 152, Pg. 41, 1944.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -1.23E+02 deg C   EXP
Boiling Point 20.1 deg C   EXP
pKa Dissociation Constant 13.57 (none) 25 EXP
log P (octanol-water) -0.34 (none)   EXP
Water Solubility 1.00E+06 mg/L 25 EXP
Vapor Pressure 902 mm Hg 25 EXP
Henry's Law Constant 6.67E-05 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.58E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.