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Substance Name: Formamide
RN: 75-12-7
UNII: 4781T907ZS
InChIKey: ZHNUHDYFZUAESO-UHFFFAOYSA-N

Molecular Formula

  • C-H3-N-O

Molecular Weight

  • 45.0407
 

Classification Codes

Classification Codes

  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Code

  • TWA (10 ppm); skin

Names and Synonyms

Name of Substance

  • Formamide

Synonyms

  • AI3-15357
  • Amid kyseliny mravenci
  • Amid kyseliny mravenci [Czech]
  • Carbamaldehyde
  • CCRIS 6240
  • EC 200-842-0
  • EINECS 200-842-0
  • Formamide
  • Formic acid, amide
  • Formimidic acid
  • HSDB 88
  • Methanamide
  • Methanoic acid, amide
  • NSC 748
  • UNII-4781T907ZS

Systematic Name

  • Formamide

Superlist Name

  • Formamide

Registry Numbers

CAS Registry Number

  • 75-12-7

FDA UNII

  • 4781T907ZS

Other Registry Numbers

  • 1156543-55-3
  • 1158234-15-1
  • 23296-41-5

System Generated Number

  • 0000075127

Structure Descriptors

InChI

1S/CH3NO/c2-1-3/h1H,(H2,2,3)

InChIKey

ZHNUHDYFZUAESO-UHFFFAOYSA-N

Smiles

C(=O)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 1500mg/kg (1500mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
frog LDLo subcutaneous 30mg/kg (30mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
guinea pig LD50 intraperitoneal 1250mg/kg (1250mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 9, Pg. 163, 1967.
mammal (species unspecified) LD50 oral 3150mg/kg (3150mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mouse LD50 intraperitoneal 2450mg/kg (2450mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 230, Pg. 559, 1957.
mouse LD50 oral 3150mg/kg (3150mg/kg)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 11, Pg. 86, 1969.
rabbit LD50 skin 17gm/kg (17000mg/kg)   National Technical Information Service. Vol. OTS0528421,
rat LC50 inhalation > 3900ppm/6H (3900ppm)   National Technical Information Service. Vol. OTS0528421,
rat LD skin > 13500mg/kg (13500mg/kg)   Polish Journal of Pharmacology and Pharmacy. Vol. 32, Pg. 223, 1980.
rat LD50 intraperitoneal 5700mg/kg (5700mg/kg)   Toxicology and Applied Pharmacology. Vol. 26, Pg. 596, 1973.
rat LD50 oral 5577mg/kg (5577mg/kg) KIDNEY, URETER, AND BLADDER: INCONTINENCE

BEHAVIORAL: ATAXIA

AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 9, Pg. 163, 1967.
rat LD50 subcutaneous > 4gm/kg (4000mg/kg)   Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle Pathologie. Vol. 257, Pg. 296, 1967.
rat LD50 unreported 3gm/kg (3000mg/kg)   Experientia. Vol. 29, Pg. 225, 1973.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 2.55 deg C   EXP
Boiling Point 220 deg C   EXP
pKa Dissociation Constant -0.48 (none) 25 EXP
log P (octanol-water) -1.51E+00 (none)   EXP
Water Solubility 1.00E+06 mg/L 25 EXP
Vapor Pressure 0.061 mm Hg 25 EXP
Henry's Law Constant 1.39E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.00E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.