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Substance Name: Chlorodifluoromethane
RN: 75-45-6
UNII: ZFO627O6CN
InChIKey: VOPWNXZWBYDODV-UHFFFAOYSA-N

Molecular Formula

  • C-H-Cl-F2

Molecular Weight

  • 86.4679
 

Classification Codes

Classification Codes

  • Mutation Data
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 3
  • TWA (1000 ppm); Not classifiable as a human carcinogen

Names and Synonyms

Name of Substance

  • Chlorodifluoromethane
  • Chlorofluorocarbon 22
  • Fluorocarbon 22
  • Hydrochlorofluorocarbon 22
  • Methane, chlorodifluoro-
  • Propellant 22

Synonyms

  • 4-01-00-00032 (Beilstein Handbook Reference)
  • Algeon 22
  • Algofrene 22
  • Algofrene type 6
  • Arcton 22
  • Arcton 4
  • BRN 1731036
  • CCRIS 858
  • CFC 22
  • Chlorofluorocarbon 22
  • Daiflon 22
  • Difluorochloromethane
  • Difluoromonochloromethane
  • Dymel 22
  • EC 200-871-9
  • EINECS 200-871-9
  • Electro-CF 22
  • Eskimon 22
  • F 22
  • F 22 (halocarbon)
  • FC 22
  • FKW 22
  • Flugene 22
  • Fluorocarbon-22
  • Forane 22
  • Forane 22 B
  • Freon 22
  • Frigen
  • Frigen 22
  • Genetron 22
  • Haltron 22
  • HCFC 22
  • HCFC-22
  • HFA-22
  • HSDB 143
  • Hydrochlorofluorocarbon 22
  • Isceon 22
  • Isotron 22
  • Khladon 22
  • Methane, chlorodifluoro-
  • Monochlorodifluoromethane
  • Propellant 22
  • R 22 (refrigerant)
  • R-22
  • Racon 22
  • Refrigerant R 22
  • Ucon 22
  • UNII-ZFO627O6CN

Systematic Names

  • Chlorodifluoromethane
  • Methane, chlorodifluoro-

Superlist Names

  • Chlorodifluoromethane
  • Chlorodifluoromethane [R22] [UN1018] [Nonflammable gas]
  • HCFC-22
  • Methane, chlorodifluoro-
  • Monochlorodifluoromethane
  • R22
  • R22 [UN1018] [Nonflammable gas]
  • UN1018

Registry Numbers

CAS Registry Number

  • 75-45-6

FDA UNII

  • ZFO627O6CN

Other Registry Numbers

  • 134191-96-1
  • 191542-01-5
  • 73666-77-0

System Generated Number

  • 0000075456

Structure Descriptors

InChI

1S/CHClF2/c2-1(3)4/h1H

InChIKey

VOPWNXZWBYDODV-UHFFFAOYSA-N

Smiles

C(F)(F)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LCLo inhalation 70pph (700000ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Toxicology and Applied Pharmacology. Vol. 2, Pg. 363, 1960.
guinea pig LCLo inhalation 30pph/2H (300000ppm) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. Vol. 21, Pg. 149, 1971.
mouse LC50 inhalation 1380gm/m3/2H (1380000mg/m3) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Trudy Leningradskogo Sanitarno-Gigienicheskogo Meditsinskogo Instituta. Vol. 75, Pg. 241, 1963.
rat LC50 inhalation 35pph/15M (350000ppm) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA
Human Toxicology. Vol. 1, Pg. 239, 1982.
rat LD oral > 43200ug/kg (43.2mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(8), Pg. 69, 1983.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -1.57E+02 deg C   EXP
Boiling Point -4.07E+01 deg C   EXP
log P (octanol-water) 1.08 (none)   EXP
Water Solubility 2770 mg/L 25 EXP
Vapor Pressure 7250 mm Hg 25 EXP
Henry's Law Constant 0.0406 atm-m3/mole 22 EXP
Atmospheric OH Rate Constant 4.68E-15 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.