Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: 4-Epianhydrotetracycline
RN: 7518-17-4
UNII: 680VDL31MX
InChIKey: CXCVEERYMJZMMM-WPINSWFRSA-N

Note

  • Impurity in pahrmaceutical preparations of tetracycline.

Molecular Formula

  • C22-H22-N2-O7

Molecular Weight

  • 426.4228
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • 4-Epianhydrotetracycline

Name of Substance

  • 4-Epianhydrotetracycline

Synonyms

  • (4R-(4alpha,4abeta,12abeta))-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide
  • 4-epi-5a,6-Anhydrotetracycline
  • 4-Epianhydrotetracycline
  • Epianhydrotetracycline
  • UNII-680VDL31MX

Systematic Name

  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, (4R-(4alpha,4abeta,12abeta))-

Registry Numbers

CAS Registry Number

  • 7518-17-4

FDA UNII

  • 680VDL31MX

Other Registry Numbers

  • 13366-25-1
  • 1665-57-2
  • 4907-76-0

System Generated Number

  • 0007518174

Structure Descriptors

InChI

1S/C22H22N2O7/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30)/t11-,16+,22-/m0/s1

InChIKey

CXCVEERYMJZMMM-WPINSWFRSA-N

Smiles

Cc1c2cccc(c2c(c3c1C[C@H]4[C@H](C(=C(C(=O)[C@]4(C3=O)O)C(=O)N)O)N(C)C)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 193mg/kg (193mg/kg)   Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. Vol. 13, Pg. 244, 1966.
mouse LD50 unreported 29200ug/kg (29.2mg/kg)   "Evaluation of Embryotoxicity, Mutagenicity and Carcinogenicity Risks In New Drugs, Proceedings of the Symposium on Toxicological Testing for Safety of New Drugs, 3rd, Prague, 1976," Benesova, O., et al., eds., Prague, Czechoslovakia, Univerzita Karlova, 1979Vol. -, Pg. 55, 1979.