Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Moxonidine [USAN:INN:BAN]
RN: 75438-57-2
UNII: CC6X0L40GW
InChIKey: WPNJAUFVNXKLIM-UHFFFAOYSA-N

Classification Codes

  • Antihypertensive
  • Antihypertensive Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Human Data
  • Treatment of Congestive Heart Failure
  • Treatment of Type 2 Diabetes (Centrally Acting Sympatholytic)

Molecular Formula

  • C9-H12-Cl-N5-O

Molecular Weight

  • 241.6808
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Moxonidine
  • Moxonidine [USAN:INN:BAN]

Synonyms

  • 4-Chloro-5-(2-imidazolidinyldeneamino)-6-methoxy-2-methylpyrimidine
  • 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
  • 5-Pyrimidinamine, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-
  • BDF 5895
  • BDF5896
  • BE 5895
  • BE5895
  • Cynt
  • LY 326869
  • LY326869
  • Monoxidine [common misspelling of Moxonidine]
  • Moxonidina
  • Moxonidina [Spanish]
  • Moxonidine
  • Moxonidinum
  • Moxonidinum [Latin]
  • Norcynt
  • Nucynt
  • UNII-CC6X0L40GW

Systematic Names

  • 4-Chloro-5-(2-imidazolin-2-ylamino)-6-methoxy-2-methylpyrimidine
  • 5-Pyrimidinamine, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-

Registry Numbers

CAS Registry Number

  • 75438-57-2

FDA UNII

  • CC6X0L40GW

System Generated Number

  • 0075438572

Structure Descriptors

InChI

1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15)

InChIKey

WPNJAUFVNXKLIM-UHFFFAOYSA-N

Smiles

c1(c(nc(C)nc1Cl)OC)\N=C1\NCCN1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 780mg/kg/39W- (780mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

LIVER: "JAUNDICE, CHOLESTATIC"
Lancet. Vol. 350, Pg. 1822, 1997.