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Substance Name: Fomepizole [USAN:INN:BAN]
RN: 7554-65-6
UNII: 83LCM6L2BY
InChIKey: RIKMMFOAQPJVMX-UHFFFAOYSA-N
Note
- Alcohol dehyrogenase inhibitor.
Molecular Formula
- C4-H6-N2
Molecular Weight
- 82.1054
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Antidote (Alcohol Dehydrogenase Inhibitor)
- Antidotes
- Enzyme Inhibitors
- Protective Agents
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Names and Synonyms
Name of Substance
- Fomepizole
- Fomepizole [USAN:INN:BAN]
MeSH Heading
- Fomepizole
Synonyms
- 4-Methylpyrazol
- 4-Methylpyrazole
- 4-MP
- 5-23-05-00031 (Beilstein Handbook Reference)
- Antizol
- Antizol-vet
- BRN 0105204
- EC 231-445-0
- EINECS 231-445-0
- Fomepizol
- Fomepizol [INN-Spanish]
- Fomepizole
- Fomepizolum
- Fomepizolum [INN-Latin]
- UNII-83LCM6L2BY
Systematic Names
- 1H-Pyrazole, 4-methyl-
- 4-Methylpyrazole
- Pyrazole, 4-methyl-
Registry Numbers
CAS Registry Number
- 7554-65-6
FDA UNII
- 83LCM6L2BY
System Generated Number
- 0007554656
Structure Descriptors
InChI
1S/C4H6N2/c1-4-2-5-6-3-4/h2-3H,1H3,(H,5,6)InChIKey
RIKMMFOAQPJVMX-UHFFFAOYSA-NSmiles
c1(cn[nH]c1)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 310mg/kg (310mg/kg) | Experientia. Vol. 28, Pg. 1198, 1972. | |
| mouse | LD50 | oral | 640mg/kg (640mg/kg) | Experientia. Vol. 28, Pg. 1198, 1972. | |
| rat | LD50 | intravenous | 310mg/kg (310mg/kg) | Experientia. Vol. 28, Pg. 1198, 1972. | |
| rat | LD50 | oral | 534mg/kg (534mg/kg) | Experientia. Vol. 28, Pg. 1198, 1972. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Boiling Point | 206 | deg C | EXP | |
| log P (octanol-water) | 0.610 | (none) | EST | |
| Atmospheric OH Rate Constant | 9.41E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.