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Substance Name: Rimcazole hydrochloride [USAN]
RN: 75859-03-9
UNII: 2XAC11FCQ4
InChIKey: ZWHRZGHGYMUSRM-VWDRLOGHSA-N

Classification Codes

  • Antipsychotic
  • Drug / Therapeutic Agent

Molecular Formula

  • C21-H27-N3.2Cl-H

Molecular Weight

  • 394.387
 
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Names and Synonyms

Name of Substance

  • Rimcazole hydrochloride [USAN]

Synonyms

  • 9-(3-(cis-3,5-Dimethyl-1-piperazinyl)propyl)carbazole dihydrochloride
  • 9H-Carbazole, 9-(3-(3,5-dimethyl-1-piperazinyl)propyl)-, dihydrochloride, cis-
  • BW 234U dihydrochloride
  • cis-9-(3-(3,5-Dimethyl-1-piperazinyl)propyl)-9H-carbazole dihydrochloride
  • Rimcazole HCl
  • Rimcazole hydrochloride
  • UNII-2XAC11FCQ4

Systematic Name

  • 9H-Carbazole, 9-(3-(3,5-dimethyl-1-piperazinyl)propyl)-, dihydrochloride, cis-

Registry Numbers

CAS Registry Number

  • 75859-03-9

FDA UNII

  • 2XAC11FCQ4

System Generated Number

  • 0075859039

Molecular Formulas

Molecular Formula

  • C21-H27-N3.2Cl-H

Molecular Formula Fragments

  • C21-H27-N3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C21H27N3.2ClH/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24;;/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3;2*1H/t16-,17+;;

InChIKey

ZWHRZGHGYMUSRM-VWDRLOGHSA-N

Smiles

n1(c2c(cccc2)c2c1cccc2)CCCN1C[C@H](N[C@H](C1)C)C.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 185mg/kg (185mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 34, Pg. 388, 1982.
mouse LD50 oral 816mg/kg (816mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 34, Pg. 388, 1982.
rat LD50 intraperitoneal 80mg/kg (80mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 34, Pg. 388, 1982.
rat LD50 oral 907mg/kg (907mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 34, Pg. 388, 1982.