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Substance Name: N-Nitroso-N-ethylurea
RN: 759-73-9
UNII: P8M1T4190R
InChIKey: FUSGACRLAFQQRL-UHFFFAOYSA-N

Note

  • A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.

Molecular Formula

  • C3-H7-N3-O2

Molecular Weight

  • 117.107
 

Classification Codes

Classification Codes

  • Alkylating Agents
  • Mutation Data
  • Noxae
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 2A
  • Reasonably Anticipated to be a Carcinogen
  • Reportable Quantity (RQ) = 1 lb

Names and Synonyms

Name of Substance

  • Ethylnitrosourea
  • N-Ethyl-N-nitrosourea
  • N-Nitroso-N-ethylurea

MeSH Heading

  • Ethylnitrosourea

Synonyms

  • 1-Ethyl-1-nitrosomocovina
  • 1-Ethyl-1-nitrosomocovina [Czech]
  • 1-Ethyl-1-nitrosourea
  • 3-04-00-00233 (Beilstein Handbook Reference)
  • AENH
  • AENH [German]
  • Aethylnitroso-harnstoff
  • Aethylnitroso-harnstoff [German]
  • ANH
  • ANH [German]
  • BRN 1761174
  • Carbamide, N-ethyl-N-nitroso-
  • CCRIS 302
  • EINECS 212-072-2
  • ENU
  • Ethyl nitrosourea
  • Ethylnitrosourea
  • HSDB 5111
  • N-Ethyl-N-nitosourea
  • N-Ethyl-N-nitroso carbamide
  • N-Ethyl-N-nitroso-urea
  • N-Ethylnitrosourea
  • N-Nitroso-N-ethylurea
  • N-Nitrosoethylurea
  • NE-Urea
  • NEU
  • Nitrosoethylurea
  • NSC 45403
  • RCRA waste number U176
  • UNII-P8M1T4190R
  • Urea, 1-ethyl-1-nitroso-
  • Urea, N-ethyl-N-nitroso-

Systematic Names

  • N-Ethyl-N-nitrosourea
  • Urea, 1-ethyl-1-nitroso-
  • Urea, N-ethyl-N-nitroso-

Superlist Names

  • ENU
  • N-Ethyl-N-nitrosourea
  • N-Nitroso-N-ethylurea
  • RCRA waste no. U176
  • Urea, N-ethyl-N-nitroso-

Registry Numbers

CAS Registry Number

  • 759-73-9

FDA UNII

  • P8M1T4190R

Other Registry Number

  • 2151-05-5

System Generated Number

  • 0000759739

Structure Descriptors

InChI

1S/C3H7N3O2/c1-2-6(5-8)3(4)7/h2H2,1H3,(H2,4,7)

InChIKey

FUSGACRLAFQQRL-UHFFFAOYSA-N

Smiles

N(C(N)=O)(CC)N=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 490mg/kg (490mg/kg)   Mutation Research. Vol. 223, Pg. 377, 1989.
mouse LD50 oral 960mg/kg (960mg/kg)   Mutation Research. Vol. 223, Pg. 377, 1989.
rat LD50 intravenous 240mg/kg (240mg/kg)   Nature. Vol. 222, Pg. 1064, 1969.
rat LD50 oral 300mg/kg (300mg/kg)   Proceedings of the International Symposium of the Princess Takamatsu Cancer Research Fund. Vol. 2, Pg. 73, 1972.
rat LD50 subcutaneous 240mg/kg (240mg/kg)   Zeitschrift fuer Krebsforschung. Vol. 74, Pg. 141, 1970.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 99 dec deg C   EXP
log P (octanol-water) 0.23 (none)   EXP
Water Solubility 1.30E+04 mg/L 25 EXP
Vapor Pressure 0.018 mm Hg 25 EST
Henry's Law Constant 1.32E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 5.00E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.