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Substance Name: Camphor [USP]
RN: 76-22-2
UNII: 5TJD82A1ET
InChIKey: DSSYKIVIOFKYAU-XCBNKYQSSA-N
Note
- A bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infective agent.
Molecular Formula
- C10-H16-O
Molecular Weight
- 152.2354
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Anti-Infective Agents
- Anti-Infective Agents, Local
- Antipruritic
- Drug / Therapeutic Agent
- Fungicide, Bactericide, Wood Preservative
- Human Data
- Mutation Data
- Natural Product
- Tumor Data
Superlist Classification Codes
- TWA (2 ppm); STEL (3 ppm); Not classifiable as a human carcinogen
- TWA 2 mg/m3
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Other Resources (Internet Locators)
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Names and Synonyms
Name of Substance
- 1,7,7-Trimethylbicyclo(2.2.1)heptan-2-one
- 2-Bornanone
- Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-
- Camphor
- Camphor [USP]
- Gum camphor
- Mulberry roots
MeSH Heading
- Camphor
Synonyms
- 0-07-00-00135 (Beilstein Handbook Reference)
- 1,7,7-Trimethylbicyclo(2.2.1)-2-heptanone
- 1,7,7-Trimethylnorcamphor
- 2-Bornanone
- 2-Camphanone
- 2-Kamfanon
- 2-Kamfanon [Czech]
- 2-Keto-1,7,7-trimethylnorcamphane
- 4-07-00-00213 (Beilstein Handbook Reference)
- AI3-18783
- Alphanon
- Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-
- Bicyclo(2.2.1)heptane-2-one, 1,7,7-trimethyl-
- Bornane, 2-oxo-
- BRN 1907611
- BRN 3196099
- Camphor
- Camphor, synthetic
- Caswell No. 155
- Cinnamomum camphora
- DL-Camphor
- EC 200-945-0
- EINECS 200-945-0
- EINECS 244-350-4
- EPA Pesticide Chemical Code 015602
- Gum camphor
- HSDB 37
- Huile de camphre
- Huile de camphre [French]
- Kampfer
- Kampfer [German]
- Matricaria camphor
- Norcamphor, 1,7,7-trimethyl-
- Root bark oil
- Spirit of camphor
- UNII-5TJD82A1ET
- Zang Qi
Systematic Names
- (+-)-Camphor
- Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-
- Bornan-2-one
- Camphor
- DL-Bornan-2-one
Superlist Names
- Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-
- Camphor
- Camphor, synthetic
- Camphor, synthetic [UN2717] [Flammable solid]
- UN2717
Mixture Names
- Campho-Phenique Cold Sore Gel
- Campho-Phenique Gel
- Campho-Phenique Liquid
- Heet
- Sarna
Registry Numbers
CAS Registry Number
- 76-22-2
FDA UNII
- 5TJD82A1ET
Other Registry Numbers
- 21368-68-3
- 48113-22-0
- 8013-55-6
- 8022-77-3
System Generated Number
- 0000076222
Structure Descriptors
InChI
InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1InChIKey
DSSYKIVIOFKYAU-XCBNKYQSSA-NSmiles
CC1(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | intraperitoneal | 400mg/kg (400mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
child | LDLo | unreported | 100mg/kg (100mg/kg) | Yakkyoku. Pharmacy. Vol. 31, Pg. 1499, 1980. | |
child | TDLo | oral | 51mg/kg (51mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | American Journal of Emergency Medicine. Vol. 7, Pg. 41, 1989. |
dog | LDLo | oral | 800mg/kg (800mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
frog | LDLo | subcutaneous | 240mg/kg (240mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE | Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903. |
infant | LDLo | oral | 70mg/kg (70mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | American Journal of Pathology. Vol. 30, Pg. 857, 1954. |
man | LDLo | unreported | 29mg/kg (29mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
mouse | LCLo | inhalation | 400mg/m3/3H (400mg/m3) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 22(11), Pg. 83, 1957. |
mouse | LD50 | intraperitoneal | 3gm/kg (3000mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: REGIDITY | American Journal of Pathology. Vol. 30, Pg. 857, 1954. |
mouse | LD50 | oral | 1310mg/kg (1310mg/kg) | Shika Gakuho. Journal of Dentistry. Vol. 75, Pg. 934, 1975. | |
mouse | LDLo | subcutaneous | 200mg/kg (200mg/kg) | BEHAVIORAL: EXCITEMENT | "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933Vol. -, Pg. -, 1933. |
rabbit | LDLo | oral | 2gm/kg (2000mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: REGIDITY | American Journal of Pathology. Vol. 30, Pg. 857, 1954. |
rat | LD50 | subcutaneous | 70mg/kg (70mg/kg) | "Ueber die Pharmakologische Wirkung eines dem Pentamethylentetrazol Vol. -, Pg. -, 1934. | |
rat | LDLo | intraperitoneal | 900mg/kg (900mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 275, 1939. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 180 | deg C | EXP | |
Boiling Point | 204 | deg C | EXP | |
log P (octanol-water) | 2.38 | (none) | EXP | |
Water Solubility | 1600 | mg/L | 25 | EXP |
Vapor Pressure | 0.65 | mm Hg | 25 | EXP |
Henry's Law Constant | 8.10E-05 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 9.88E-12 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.