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Substance Name: Sodium bisulfite [JAN:NF]
RN: 7631-90-5
UNII: TZX5469Z6I
InChIKey: DWAQJAXMDSEUJJ-UHFFFAOYSA-M

Note

  • Has been used externally for parasitic skin diseases and as gastrointestinal antiseptic.

Molecular Formulas

  • H-O3-S.Na
  • H2-O3-S.Na

Molecular Weight

  • 104.0609
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Anti-Infective Agents
  • Anti-Infective Agents, Local
  • Antioxidants
  • Fungicide, Bactericide, Wood Preservative
  • Mutagens
  • Mutation Data
  • Noxae
  • Protective Agents
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 3
  • Reportable Quantity (RQ) = 5000 lb
  • TWA 5 mg/m3; Not classifiable as a human carcinogen

Names and Synonyms

Name of Substance

  • Sodium acid sulfite
  • Sodium bisulfite
  • Sodium bisulfite [JAN:NF]

Synonyms

  • AI3-08582
  • Bisulfite de sodium
  • Bisulfite de sodium [French]
  • Caswell No. 750
  • CCRIS 3950
  • EC 231-548-0
  • EINECS 231-548-0
  • EPA Pesticide Chemical Code 078201
  • Fr-62
  • HSDB 724
  • Hydrogen sodium sulfite
  • Hydrogen sulfite sodium
  • Monosodium sulfite
  • NSC 60680
  • Sodium acid sulfite
  • Sodium bisulfite
  • Sodium bisulfite (1:1)
  • Sodium bisulfite (NaHSO3)
  • Sodium bisulphite
  • Sodium hydrogen sulfite
  • Sodium hydrosulfite(DOT)
  • Sodium metabisulfite
  • Sodium sulfite (NaHSO3)
  • Sodium sulhydrate
  • Sulfurous acid, monosodium salt
  • Uantax SBS
  • UNII-TZX5469Z6I

Systematic Names

  • Sodium bisulfite
  • Sodium bisulfite (1:1)
  • Sodium hydrogensulfite
  • Sodium hydrogensulphite (aqueous solution)
  • Sulfurous acid, monosodium salt
  • Sulfurous acid, sodium salt (1:1)

Superlist Names

  • Sodium bisulfite
  • Sodium hydrogen sulfite solution (45% or less)
  • Sodium hydrogen sulfite, solution
  • Sulfurous acid, monosodium salt

Registry Numbers

CAS Registry Number

  • 7631-90-5

FDA UNII

  • TZX5469Z6I

Other Registry Numbers

  • 57414-01-4
  • 69098-86-8
  • 855427-07-5
  • 855924-73-1
  • 89830-27-3
  • 91829-63-9

System Generated Number

  • 0007631905

Molecular Formulas

Molecular Formulas

  • H-O3-S.Na
  • H2-O3-S.Na

Molecular Formula Fragments

  • COMPONENT
  • H-O3-S
  • H2-O3-S
  • Na

Structure Descriptors

InChI

1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-1

InChIKey

DWAQJAXMDSEUJJ-UHFFFAOYSA-M

Smiles

[Na+].OS(=O)[O-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intraperitoneal 244mg/kg (244mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Clinical Pharmacology and Therapeutics Vol. 9, Pg. 328, 1968.
guinea pig LD50 intraperitoneal 779mg/kg (779mg/kg)   Toxicology and Applied Pharmacology. Vol. 44, Pg. 251, 1978.
hamster LD50 intraperitoneal 487mg/kg (487mg/kg)   Ceskoslovenska Hygiena. Czechoslovak Hygiene. Vol. 22, Pg. 64, 1977.
hamster LD50 intravenous 95mg/kg (95mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 101, 1951.
mouse LD50 intraperitoneal 675mg/kg (675mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Clinical Pharmacology and Therapeutics Vol. 9, Pg. 328, 1968.
mouse LD50 intravenous 130mg/kg (130mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 101, 1951.
rabbit LD50 intraperitoneal 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Clinical Pharmacology and Therapeutics Vol. 9, Pg. 328, 1968.
rabbit LD50 intravenous 65mg/kg (65mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 101, 1951.
rat LD50 intraperitoneal 475mg/kg (475mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Proceedings of the National Academy of Sciences of the United States of America. Vol. 70, Pg. 3655, 1973.
rat LD50 intravenous 115mg/kg (115mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 101, 1951.
rat LD50 oral 2gm/kg (2000mg/kg)   "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 6, Pg. 1408, 1991.