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Substance Name: Hydrofluoric acid
RN: 7664-39-3
UNII: RGL5YE86CZ
InChIKey: KRHYYFGTRYWZRS-UHFFFAOYSA-N

Note

  • Hydrofluoric acid. A solution of hydrogen fluoride in water. It is a colorless fuming liquid which can cause painful burns.

Molecular Formula

  • F-H

Molecular Weight

  • 20.0059
 

Classification Codes

Classification Codes

  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 247
  • Ceiling (3 ppm); BEI
  • Reportable Quantity (RQ) = 100 lb
  • Threshold Planning Quantity (TPQ) = 100 lb
  • TWA 3 mg/m3

Names and Synonyms

Name of Substance

  • Hydrofluoric acid

MeSH Heading

  • Hydrofluoric acid

Synonyms

  • Acide fluorhydrique
  • Acide fluorhydrique [French]
  • Acido fluorhidrico
  • Acido fluorhidrico [Spanish]
  • Acido fluoridrico
  • Acido fluoridrico [Italian]
  • Antisal 2B
  • Caswell No. 484
  • EC 231-634-8
  • EINECS 231-634-8
  • EPA Pesticide Chemical Code 045601
  • Fluorhydric acid
  • Fluorowodor
  • Fluorowodor [Polish]
  • Fluorure d'hydrogene anhydre
  • Fluorure d'hydrogene anhydre [French]
  • Fluoruro de hidrogeno anhidro
  • Fluoruro de hidrogeno anhidro [Spanish]
  • Fluorwasserstoff
  • Fluorwasserstoff [German]
  • Fluorwaterstof
  • Fluorwaterstof [Dutch]
  • HSDB 546
  • Hydrofluoric acid
  • Hydrofluoricum acidum
  • Hydrofluoride
  • Hydrogen fluoride (HF)
  • RCRA waste number U134
  • Rubigine
  • UN 1052 (anhydrous)
  • UN 1790 (solution)
  • UNII-RGL5YE86CZ

Systematic Names

  • Hydrofluoric acid
  • Hydrogen fluoride

Superlist Names

  • Hydrofluoric acid
  • Hydrofluoric acid 70% by weight or more HF
  • Hydrofluoric acid, with more than 60% strength
  • Hydrofluoric acid, with more than 60% strength [UN1790] [Corrosive]
  • Hydrofluoric acid, with not more than 60% strength
  • Hydrofluoric acid, with not more than 60% strength [UN1790] [Corrosive]
  • Hydrogen fluoride
  • Hydrogen fluoride, anhydrous
  • Hydrogen fluoride, anhydrous [UN1052] [Corrosive]
  • Hydrogen fluoride/Hydrofluoric acid (conc 50% or greater)
  • RCRA waste no. U134
  • UN1052
  • UN1790

Registry Numbers

CAS Registry Number

  • 7664-39-3

FDA UNII

  • RGL5YE86CZ

Other Registry Numbers

  • 32057-09-3
  • 326604-75-5

System Generated Number

  • 0007664393

Structure Descriptors

InChI

1S/FH/h1H

InChIKey

KRHYYFGTRYWZRS-UHFFFAOYSA-N

Smiles

F

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo subcutaneous 112mg/kg (112mg/kg)   Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 124, Pg. 133, 1937.
guinea pig LC50 inhalation 4327ppm/15M (4327ppm) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 American Industrial Hygiene Association Journal. Vol. 24, Pg. 253, 1963.
human LCLo inhalation 50ppm/30M (50ppm)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 318, 1969.
man TCLo inhalation 100mg/m3/1M (100mg/m3) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

LUNGS, THORAX, OR RESPIRATION: COUGH

SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE		 Journal of Industrial Hygiene. Vol. 16, Pg. 129, 1934.
man TDLo oral 143mg/kg (143mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"		 Journal of Toxicology, Clinical Toxicology. Vol. 35, Pg. 307, 1997.
monkey LC50 inhalation 1774ppm/1H (1774ppm) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: COMA

GASTROINTESTINAL: OTHER CHANGES		 Aerospace Medical Research Laboratory Report. Vol. TR-70-77, Pg. 1970,
mouse LC50 inhalation 342ppm/1H (342ppm) SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Journal of Combustion Toxicology. Vol. 3, Pg. 61, 1976.
mouse LDLo skin 500mg/kg (500mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: TREMOR

PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE		 Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 17, Pg. 281, 1975.
rabbit LCLo inhalation 260mg/m3/7H (260mg/m3)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 2, Pg. 716, 1950.
rat LC50 inhalation 1276ppm/1H (1276ppm) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS		 American Industrial Hygiene Association Journal. Vol. 33, Pg. 661, 1972.
rat LDLo intraperitoneal 25mg/kg (25mg/kg)   Toxicology and Applied Pharmacology. Vol. 13, Pg. 76, 1968.