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Substance Name: Thiorphan
RN: 76721-89-6
UNII: B79L7B5X3Z
InChIKey: LJJKNPQAGWVLDQ-UHFFFAOYSA-N

Note

  • A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.

Molecular Formula

  • C12-H15-N-O3-S

Molecular Weight

  • 253.32
 

Classification Codes

  • Enzyme Inhibitors
  • Protease Inhibitors
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Names and Synonyms

Name of Substance

  • Thiorphan

MeSH Heading

  • Thiorphan

Synonym

  • UNII-B79L7B5X3Z

Systematic Name

  • Glycine, N-(2-(mercaptomethyl)-1-oxo-3-phenylpropyl)-, (+-)-

Registry Numbers

CAS Registry Number

  • 76721-89-6

FDA UNII

  • B79L7B5X3Z

System Generated Number

  • 0076721896

Structure Descriptors

InChI

1S/C12H15NO3S/c14-11(15)7-13-12(16)10(8-17)6-9-4-2-1-3-5-9/h1-5,10,17H,6-8H2,(H,13,16)(H,14,15)

InChIKey

LJJKNPQAGWVLDQ-UHFFFAOYSA-N

Smiles

c1(C[C@@H](C(NCC(O)=O)=O)CS)ccccc1