Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Carbromal [INN:BAN:DCF:NF]
RN: 77-65-6
UNII: 0Y299JY9V3
InChIKey: OPNPQXLQERQBBV-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
  • Tumor Data

Molecular Formula

  • C7-H13-Br-N2-O2

Molecular Weight

  • 237.0957
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Carbromal
  • Carbromal [INN:BAN:DCF:NF]

Synonyms

  • (2-Brom-2-ethylbutyryl)harnstoff
  • (2-Bromo-2-ethylbutyryl)urea
  • (alpha-Bromo-alpha-ethylbutyryl)carbamide
  • (alpha-Bromo-alpha-ethylbutyryl)urea
  • 1-Bromo-ethyl-butyryl-urea
  • 2-Brom-2-ethylbutyrylmocovina
  • 2-Brom-2-ethylbutyrylmocovina [Czech]
  • 4-03-00-00117 (Beilstein Handbook Reference)
  • Adalin
  • Addisomnol
  • AI3-51262
  • alpha-Ethyl-alpha-bromobutyrylurea
  • BRN 1775637
  • Bromacetocarbamide
  • Bromacetocarbamidum
  • Bromadal
  • Bromdiethylacetylurea
  • Bromodiethylacetylcarbamide
  • Bromodiethylacetylurea
  • Butanamide, N-(aminocarbonyl)-2-bromo-2-ethyl-
  • Carbromal
  • Carbromalum
  • Carbromalum [INN-Latin]
  • CCRIS 124
  • Diacid
  • Dormiturin
  • EINECS 201-046-6
  • Fydalin
  • Hoggar
  • HSDB 4100
  • Karbromal
  • Kartryl
  • Mirfudorm
  • N-(Aminocarbonyl)-2-bromo-2-ethylbutanamide
  • NCI-C03805
  • Nenesin
  • NSC 49191
  • Nyctal
  • Parkosed
  • Pelidorm
  • Persomnin
  • Pianadalin
  • Planadalin
  • Servadorm
  • Somben
  • Thalambrol
  • Tildin
  • UNII-0Y299JY9V3
  • Uradal
  • Urea, (2-bromo-2-ethylbutyryl)-

Systematic Names

  • 2-Bromo-2-ethylbutyrylurea
  • Butanamide, N-(aminocarbonyl)-2-bromo-2-ethyl-
  • Carbromal
  • Urea, (2-bromo-2-ethylbutyryl)- (8CI)

Superlist Name

  • Carbromal

Mixture Name

  • Carbrital

Registry Numbers

CAS Registry Number

  • 77-65-6

FDA UNII

  • 0Y299JY9V3

System Generated Number

  • 0000077656

Structure Descriptors

InChI

1S/C7H13BrN2O2/c1-3-7(8,4-2)5(11)10-6(9)12/h3-4H2,1-2H3,(H3,9,10,11,12)

InChIKey

OPNPQXLQERQBBV-UHFFFAOYSA-N

Smiles

C(C(NC(N)=O)=O)(CC)(CC)Br

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 350mg/kg (350mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1293, 1935.
dog LDLo oral 450mg/kg (450mg/kg)   "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 278, 1989.
dog LDLo subcutaneous 300mg/kg (300mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1292, 1935.
frog LDLo subcutaneous 1667mg/kg (1667mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1293, 1935.
mouse LD50 intraperitoneal 832mg/kg (832mg/kg)   Clinical and Experimental Pharmacology and Physiology. Vol. 3, Pg. 443, 1976.
mouse LD50 oral 464mg/kg (464mg/kg)   Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,
rabbit LDLo oral 600mg/kg (600mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
Skandinavisches Archiv fuer Physiologie. Vol. 28, Pg. 193, 1913.
rat LD50 intraperitoneal 427mg/kg (427mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ATAXIA
Intensivmedizin. Vol. 17, Pg. 305, 1980.
rat LD50 intravenous 427mg/kg (427mg/kg)   Archives of Toxicology. Vol. 40, Pg. 211, 1978.
rat LD50 oral 316mg/kg (316mg/kg)   Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. Vol. NCI-E-C-72-3252, Pg. 1973,
rat LDLo unreported 350mg/kg (350mg/kg)   Journal of the American Pharmaceutical Association. Vol. 23, Pg. 788, 1934.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 118 deg C   EXP
log P (octanol-water) 1.54 (none)   EXP
Water Solubility 333 mg/L   EXP
Vapor Pressure 2.00E-07 mm Hg 25 EST
Henry's Law Constant 3.86E-11 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 4.63E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.