Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Sorivudine [USAN:INN:BAN:JAN]
RN: 77181-69-2
UNII: C7VOZ162LV
InChIKey: GCQYYIHYQMVWLT-HQNLTJAPSA-N

Classification Codes

  • Anti-Infective Agents
  • Antiviral
  • Antiviral Agents
  • Drug / Therapeutic Agent
  • Mutation Data
  • Reproductive Effect

Molecular Formula

  • C11-H13-Br-N2-O6

Molecular Weight

  • 349.1357
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Sorivudine
  • Sorivudine [USAN:INN:BAN:JAN]

Synonyms

  • (+)-1-beta-D-Arabinofuranosyl-5-((E)-2-bromovinyl)uracil
  • (E)-1-beta-D-Arabinofuranosyl-5-(2-bromoethenyl)-2,4(1H,3H)-pyrimidinedione
  • (E)-5-(2-Bromovinyl)-1-beta-D-arabinofuranosyluracil
  • (E)-5-(2-Bromovinyl)uridine
  • 1-beta-D-Arabinofuranosyl-(E)-5-(2-bromovinyl)uracil
  • 5-Bromovinyl-araU
  • ARYS-01
  • Bravavir
  • Bromovinyluridine
  • BV-Ara-U
  • CCRIS 5285
  • DRU-0136
  • Sorivudina
  • Sorivudina [INN-Spanish]
  • Sorivudine
  • Sorivudinum
  • Sorivudinum [INN-Latin]
  • SQ 32,756
  • SQ-32756
  • UNII-C7VOZ162LV
  • Usevir
  • YN-72

Systematic Names

  • (E)-5-(2-Bromovinyl)-1-beta-D-arabinofuranosyluracil
  • 2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-5-(2-bromoethenyl)-, (E)-

Registry Numbers

CAS Registry Number

  • 77181-69-2

FDA UNII

  • C7VOZ162LV

Other Registry Number

  • 80434-16-8

System Generated Number

  • 0077181692

Structure Descriptors

InChI

1S/C11H13BrN2O6/c12-2-1-5-3-14(11(19)13-9(5)18)10-8(17)7(16)6(4-15)20-10/h1-3,6-8,10,15-17H,4H2,(H,13,18,19)/b2-1+/t6-,7-,8+,10-/m1/s1

InChIKey

GCQYYIHYQMVWLT-HQNLTJAPSA-N

Smiles

n1([C@@H]2O[C@H](CO)[C@H]([C@@H]2O)O)cc(c(=O)[nH]c1=O)\C=C\Br

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 5gm/kg (5000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 925, 1990.
mouse LD50 intraperitoneal > 3gm/kg (3000mg/kg)   Drugs of the Future. Vol. 7, Pg. 458, 1982.
mouse LD50 oral > 10gm/kg (10000mg/kg)   Drugs of the Future. Vol. 7, Pg. 458, 1982.
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg)   Drugs of the Future. Vol. 7, Pg. 458, 1982.
rat LD50 intraperitoneal > 2gm/kg (2000mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 873, 1990.
rat LD50 oral > 8gm/kg (8000mg/kg) GASTROINTESTINAL: OTHER CHANGES Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 873, 1990.
rat LD50 subcutaneous > 2gm/kg (2000mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 873, 1990.