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Substance Name: Zinc Sulfate [USP]
RN: 7733-02-0
UNII: 0J6Z13X3WO
InChIKey: NWONKYPBYAMBJT-UHFFFAOYSA-L

Note

  • A compound given in the treatment of conditions associated with zinc deficiency such as acrodermatitis enteropathica. Externally, zinc sulfate is used as an astringent in lotions and eye drops. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)

Molecular Formulas

  • H2-O4-S.Zn
  • O4-S.Zn

Molecular Weight

  • 161.452
 

Classification Codes

Classification Codes

  • Astringents
  • Dermatologic Agents
  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data
  • Wood Preservative

Superlist Classification Code

  • Reportable Quantity (RQ) = 1000 lb

Names and Synonyms

Name of Substance

  • Sulfuric acid, zinc salt (1:1)
  • Zinc sulfate
  • Zinc Sulfate [USP]

MeSH Heading

  • Zinc sulfate

Synonyms

  • AI3-03967
  • Bonazen
  • Bufopto zinc sulfate
  • Caswell No. 927
  • CCRIS 3664
  • Complexonat
  • component of Phenylzin
  • EC 231-793-3
  • EINECS 231-793-3
  • EPA Pesticide Chemical Code 089001
  • HSDB 1063
  • Medizinc
  • Neozin
  • NSC 135806
  • NSC 32677
  • NU-Z
  • OP-Thal-zin
  • Optised
  • Optraex
  • Orazinc
  • Prefrin-Z
  • Salvazinc
  • Solvezinc
  • Solvezink
  • Sulfate de zinc
  • Sulfate de zinc [French]
  • Sulfuric acid zinc salt (VAN)
  • Sulfuric acid, zinc salt
  • Sulfuric acid, zinc salt (1:1)
  • UNII-0J6Z13X3WO
  • Verazinc
  • Visine-ac
  • White copperas
  • White vitriol
  • White vitriol (VAN)
  • Zinc sulfate
  • Zinc sulfate (1:1)
  • Zinc sulfate (ZnSO4)
  • Zinc sulfate anhydrous
  • Zinc sulphate
  • Zinc vitriol
  • Zinc vitriol (VAN)
  • Zinc-200
  • Zincate
  • Zinci Sulfas
  • Zincomed
  • Zincum Sulfuricum
  • Zink-Gro
  • Zinklet
  • Zinkosite

Systematic Names

  • Sulfuric acid, zinc salt (1:1)
  • Zinc sulfate
  • Zinc sulfate (1:1)
  • Zinc sulphate

Superlist Names

  • Sulfuric acid, zinc salt (1:1)
  • Zinc sulfate

Mixture Name

  • Acunol

Registry Numbers

CAS Registry Number

  • 7733-02-0

FDA UNII

  • 0J6Z13X3WO

Other Registry Numbers

  • 131315-46-3
  • 139939-71-2
  • 873788-00-2

Related Registry Number

  • 7446-20-0 (heptahydrate)

System Generated Number

  • 0007733020

Molecular Formulas

Molecular Formulas

  • H2-O4-S.Zn
  • O4-S.Zn

Molecular Formula Fragments

  • COMPONENT
  • H2-O4-S
  • O4-S
  • Zn

Structure Descriptors

InChI

1S/H2O4S.Zn/c1-5(2,3)4;/h(H2,1,2,3,4);/q;+2/p-2

InChIKey

NWONKYPBYAMBJT-UHFFFAOYSA-L

Smiles

[O-]S(=O)(=O)[O-].[Zn+2]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 66mg/kg (66mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
dog LDLo subcutaneous 78mg/kg (78mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
human TDLo oral 45mg/kg/7D-C (45mg/kg) BLOOD: NORMOCYTIC ANEMIA

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

GASTROINTESTINAL: OTHER CHANGES
British Medical Journal. Vol. 1, Pg. 754, 1978.
human TDLo oral 106mg/kg (106mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
British Medical Journal. Vol. 1, Pg. 1390, 1977.
man TDLo oral 180mg/kg/6W-I (180mg/kg) BLOOD: OTHER CHANGES JAMA, Journal of the American Medical Association. Vol. 252, Pg. 1443, 1984.
mouse LD50 intraperitoneal 29060ug/kg (29.06mg/kg)   Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.
mouse LD50 intravenous 23300ug/kg (23.3mg/kg)   Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
mouse LD50 oral 245mg/kg (245mg/kg)   Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 22, Pg. 230, 1987.
mouse LD50 subcutaneous 781mg/kg (781mg/kg) BLOOD: "CHANGES IN SERUM COMPOSITION (E.G., TP, BILIRUBIN, CHOLESTEROL)"

GASTROINTESTINAL: CHANGES IN PANCREATIC WEIGHT
Japanese Journal of Toxicology and Environmental Health. Vol. 44, Pg. 305, 1998.
rabbit LD50 oral 2gm/kg (2000mg/kg)   International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
rabbit LDLo intravenous 23mg/kg (23mg/kg)   Toxicology and Applied Pharmacology. Vol. 9, Pg. 269, 1966.
rabbit LDLo subcutaneous 300mg/kg (300mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LD50 intraperitoneal 196mg/kg (196mg/kg)   Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
rat LD50 intravenous 69900ug/kg (69.9mg/kg)   Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
rat LD50 oral 1710mg/kg (1710mg/kg)   Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
rat LDLo subcutaneous 330mg/kg (330mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
women TDLo oral 3120mg/kg/43W (3120mg/kg) BLOOD: MICROCYTOSIS WITH OR WITHOUT ANEMIA

BLOOD: AGRANULOCYTOSIS
Gastroenterology. Vol. 94, Pg. 508, 1988.