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Substance Name: AMPA, D,L-
RN: 77521-29-0
UNII: J090588E6X
InChIKey: UUDAMDVQRQNNHZ-UHFFFAOYSA-N

Note

  • An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Molecular Formula

  • C7-H10-N2-O4

Molecular Weight

  • 186.166
 

Classification Codes

  • Excitatory Amino Acid Agents
  • Excitatory Amino Acid Agonists
  • Neurotransmitter Agents
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Names and Synonyms

Results Name

  • AMPA, D,L-

Name of Substance

  • alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

MeSH Heading

  • alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

Synonyms

  • (+-)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
  • (R,S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
  • alpha-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid
  • alpha-Amino-2,3-dihydro-5-methyl-3-oxoisoxazolepropionic acid
  • alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
  • AMPA
  • AMPA (pharmaceutical)
  • D,L-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
  • dl-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
  • gamma-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
  • UNII-J090588E6X

Systematic Name

  • 4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-

Registry Numbers

CAS Registry Number

  • 77521-29-0

FDA UNII

  • J090588E6X

Other Registry Numbers

  • 110592-37-5
  • 126632-03-9
  • 133481-32-0
  • 139261-99-7
  • 139559-02-7
  • 74341-63-2
  • 78729-80-3
  • 79697-77-1
  • 81323-87-7
  • 83354-19-2
  • 85506-19-0
  • 86495-63-8
  • 92614-50-1

System Generated Number

  • 0077521290

Structure Descriptors

InChI

1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)

InChIKey

UUDAMDVQRQNNHZ-UHFFFAOYSA-N

Smiles

Cc1onc(O)c1CC(N)C(=O)O