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Substance Name: Ataluren [USAN:INN]
RN: 775304-57-9
UNII: K16AME9I3V
InChIKey: OOUGLTULBSNHNF-UHFFFAOYSA-N

Note

  • Overrides nonsense stop translation signals to yield full-length proteins; may prove useful in treating cystic fibrosis and Duchenne muscular dystrophy.

Molecular Formula

  • C15-H9-F-N2-O3

Molecular Weight

  • 284.2451
 

Classification Codes

  • Treatment of Disorders Caused by Nonsense (Premature Stop Codon)
  • Treatment of Disorders Caused by Nonsense (Premature Stop Codon) Mutations
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Names and Synonyms

Name of Substance

  • Ataluren
  • Ataluren [USAN:INN]

Synonyms

  • 3-(5-(2-Fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoic acid
  • Ataluren
  • PTC 124
  • PTC-124
  • PTC124
  • Translarna
  • UNII-K16AME9I3V

Systematic Name

  • Benzoic acid, 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)-

Registry Numbers

CAS Registry Number

  • 775304-57-9

FDA UNII

  • K16AME9I3V

Other Registry Number

  • 918899-30-6

System Generated Number

  • 0775304579

Structure Descriptors

InChI

1S/C15H9FN2O3/c16-12-7-2-1-6-11(12)14-17-13(18-21-14)9-4-3-5-10(8-9)15(19)20/h1-8H,(H,19,20)

InChIKey

OOUGLTULBSNHNF-UHFFFAOYSA-N