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Substance Name: Cupric Sulfate [USP]
RN: 7758-99-8
UNII: LRX7AJ16DT
InChIKey: JZCCFEFSEZPSOG-UHFFFAOYSA-L

Note

  • A sulfate salt of copper. It is a potent emetic and is used as an antidote for poisoning by phosphorus. It also can be used to prevent the growth of algae.

Molecular Formulas

  • Cu-S-O4.5H2-O
  • Cu.H2-O4-S.5H2-O
  • O4-S.Cu.5H2-O

Molecular Weight

  • 249.682
 

Classification Codes

  • Agricultural Chemical
  • Antidote (to Phosphorus)
  • Antidotes
  • Autonomic Agents
  • Central Nervous System Agents
  • Emetics
  • Fungicide, Bactericide, Wood Preservative
  • Gastrointestinal Agents
  • Herbicide
  • Human Data
  • Mutation Data
  • Peripheral Nervous System Agents
  • Protective Agents
  • Tumor Data

Names and Synonyms

Name of Substance

  • Copper(II) sulfate, pentahydrate
  • Cupric Sulfate [USP]

MeSH Heading

  • Copper Sulfate

Synonyms

  • Blue copper AS
  • Blue Copperas
  • Blue Vicking
  • Blue vitriol
  • Bluestone
  • Calcanthite
  • Caswell No. 256
  • CCRIS 5556
  • Copper sulfate (CuSO4) pentahydrate
  • Copper sulfate pentahydrate
  • Copper(2+) sulfate (1:1) pentahydrate
  • Copper(2+) sulfate pentahydrate
  • Copper(II) sulfate pentahydrate
  • Cupric sulfate
  • Cupric sulfate pentahydrate
  • EC 231-847-6
  • EPA Pesticide Chemical Code 024401
  • HSDB 2968
  • Kupfersulfat-pentahydrat
  • Kupfersulfat-pentahydrat [German]
  • Kupfervitriol
  • Kupfervitriol [German]
  • Roman vitriol
  • Salzburg vitriol
  • Sentry AQ mardel coppersafe
  • Sulfuric acid, copper(2+) salt, pentahydrate
  • Triangle
  • UNII-LRX7AJ16DT
  • Vencedor

Systematic Names

  • Copper sulfate pentahydrate
  • Copper sulphate
  • Sulfuric acid copper(2+) salt (1:1), pentahydrate
  • Sulfuric acid, copper(2+) salt (1:1), pentahydrate

Superlist Names

  • Copper sulfate, pentahydrate
  • Cupric sulfate (pentahydrate)

Registry Numbers

CAS Registry Number

  • 7758-99-8

FDA UNII

  • LRX7AJ16DT

Other Registry Numbers

  • 17829-58-2
  • 80867-41-0

System Generated Number

  • 0007758998

Molecular Formulas

Molecular Formulas

  • Cu-S-O4.5H2-O
  • Cu.H2-O4-S.5H2-O
  • O4-S.Cu.5H2-O

Molecular Formula Fragments

  • COMPONENT
  • Cu
  • Cu-S-O4
  • H2-O
  • H2-O4-S
  • O4-S

Structure Descriptors

InChI

1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2

InChIKey

JZCCFEFSEZPSOG-UHFFFAOYSA-L

Smiles

S(=O)(=O)([O-])[O-].O.O.O.O.O.[Cu+2]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LDLo oral 300mg/kg (300mg/kg)   Australian Veterinary Journal. Vol. 16, Pg. 147, 1940.
bird - wild LDLo oral 300mg/kg (300mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Australian Veterinary Journal. Vol. 16, Pg. 147, 1940.
dog LDLo oral 60mg/kg (60mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
domestic animals - goat/sheep LDLo oral 5mg/kg (5mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: HEMORRHAGE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Comparative Pathology. Vol. 82, Pg. 47, 1972.
duck LDLo oral 600mg/kg (600mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA
Australian Veterinary Journal. Vol. 16, Pg. 147, 1940.
guinea pig LDLo subcutaneous 62mg/kg (62mg/kg) BEHAVIORAL: COMA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
British Medical Journal. Vol. 2, Pg. 217, 1913.
human LDLo oral 1088mg/kg (1088mg/kg) BEHAVIORAL: COMA

BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA
Indian Practitioner. Vol. 18, Pg. 807, 1965.
human TDLo oral 272mg/kg (272mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA
Indian Practitioner. Vol. 18, Pg. 807, 1965.
mammal (species unspecified) LD50 intraperitoneal 7500ug/kg (7.5mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING
Journal of Animal Science. Vol. 55, Pg. 337, 1982.
man LDLo unreported 221mg/kg (221mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TDLo oral 429mg/kg (429mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

BEHAVIORAL: SLEEP
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 41, Pg. 193, 1999.
mouse LD50 intraperitoneal 33mg/kg (33mg/kg)   Biochemical Pharmacology. Vol. 14, Pg. 289, 1965.
pigeon LDLo oral 1gm/kg (1000mg/kg)   Australian Veterinary Journal. Vol. 16, Pg. 147, 1940.
pigeon LDLo oral 1gm/kg (1000mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Australian Veterinary Journal. Vol. 16, Pg. 147, 1940.
rat LD50 intraperitoneal 18700ug/kg (18.7mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(4), Pg. 78, 1988.
rat LD50 oral 300mg/kg (300mg/kg)   "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revisionVol. 2, Pg. 182, 1977.
rat LD50 skin > 2gm/kg (2000mg/kg)   Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 18, Pg. S161, 1993.