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Substance Name: Iobenguane I 131 [USAN:USP]
RN: 77679-27-7
UNII: Q461L7AK4R
InChIKey: PDWUPXJEEYOOTR-JRGAVVOBSA-N

Note

  • A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.

Molecular Formula

  • C8-H10-I-N3

Molecular Weight

  • 279.188
 

Classification Codes

  • Antineoplastic Agents
  • Diagnostic Aid
  • Enzyme Inhibitors
  • Indicators and Reagents
  • Radioactive Agent
  • Radiopharmaceuticals

Names and Synonyms

Name of Substance

  • Iobenguane (131I) [INN]
  • Iobenguane I 131 [USAN:USP]

MeSH Heading

  • 3-Iodobenzylguanidine

Synonyms

  • (m-((sup 131)I)Iodobenzyl)guanidine
  • 131I-MIBG
  • Azedra
  • Guanidine, ((3-(iodo-(sup 131)I)phenyl)methyl)-
  • I-131 MIBG
  • Iobeguane I 131
  • Iobenguane ((sup 131)I)
  • Iobenguane (131I)
  • Iobenguane I 131
  • Iobenguane I131
  • Iobenguano (131 I)
  • Iobenguano (131 I) [Spanish]
  • Iobenguanum (131 I)
  • Iobenguanum (131 I) [Latin]
  • meta-Iodobenzylguanidine (MIBG) labeled with iodine-131
  • MIBG-(131 I)
  • Ultratrace iobenguane I131
  • UNII-Q461L7AK4R

Systematic Names

  • (m-Iodo-(sup 131)I-benzyl)guanidine
  • Guanidine, ((3-iodo-131I)phenyl)methyl)-

Registry Numbers

CAS Registry Number

  • 77679-27-7

FDA UNII

  • Q461L7AK4R

System Generated Number

  • 0077679277

Structure Descriptors

InChI

InChI=1S/C8H10IN3/c9-7-3-1-2-6(4-7)5-12-8(10)11/h1-4H,5H2,(H4,10,11,12)/i9+4

InChIKey

PDWUPXJEEYOOTR-JRGAVVOBSA-N

Smiles

NC(=N)NCc1cccc([131I])c1