Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-1-(3-(4-phenyl-1-piperazinyl)propyl)-, monohydrochloride
RN: 77778-70-2
InChIKey: VFUDGTGISCQKOY-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C28-H29-Cl-N4-O.Cl-H

Molecular Weight

  • 509.478
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Synonyms

  • 7-Chloro-5-phenyl-1-(3-(3-phenylpiperazino)propyl)-1,3-dihydro-1,4-benzodiazepin-2-one HCl
  • VUFB-9069

Systematic Name

  • 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-1-(3-(4-phenyl-1-piperazinyl)propyl)-, monohydrochloride

Registry Numbers

CAS Registry Number

  • 77778-70-2

System Generated Number

  • 0077778702

Molecular Formulas

Molecular Formula

  • C28-H29-Cl-N4-O.Cl-H

Molecular Formula Fragments

  • C28-H29-Cl-N4-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C28H29ClN4O.ClH/c29-23-12-13-26-25(20-23)28(22-8-3-1-4-9-22)30-21-27(34)33(26)15-7-14-31-16-18-32(19-17-31)24-10-5-2-6-11-24;/h1-6,8-13,20H,7,14-19,21H2;1H

InChIKey

VFUDGTGISCQKOY-UHFFFAOYSA-N

Smiles

c1ccc(cc1)C2=NCC(=O)N(c3c2cc(cc3)Cl)CCCN4CCN(CC4)c5ccccc5.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo oral 1gm/kg (1000mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SLEEP

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Collection of Czechoslovak Chemical Communications. Vol. 45, Pg. 3593, 1980.
rat LDLo oral 1gm/kg (1000mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS
Collection of Czechoslovak Chemical Communications. Vol. 45, Pg. 3593, 1980.