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Substance Name: Tetraethyl lead
RN: 78-00-2
UNII: 13426ZWT6A
InChIKey: MRMOZBOQVYRSEM-UHFFFAOYSA-N

Note

  • A highly toxic compound used as a gasoline additive. It causes acute toxic psychosis or chronic poisoning if inhaled or absorbed through the skin.

Molecular Formula

  • C8-H20-Pb

Molecular Weight

  • 323.446
 

Classification Codes

Classification Codes

  • Human Data
  • Mutation Data
  • Organometallic
  • Reproductive Effect
  • TSCA Flag T (Subject to the Section 4 Test Rule under TSCA)
  • Tumor Data

Superlist Classification Codes

  • Reportable Quantity (RQ) = 10 lb
  • Threshold Planning Quantity (TPQ) = 100 lb
  • TWA 0.075 mg/m3; skin
  • TWA 0.1 mg/m3; skin; Not classifiable as a human carcinogen

Names and Synonyms

Name of Substance

  • Tetraethyl lead

MeSH Heading

  • Tetraethyl lead

Synonyms

  • 4-04-00-04349 (Beilstein Handbook Reference)
  • BRN 3903146
  • CCRIS 1565
  • Czteroetylek olowiu
  • Czteroetylek olowiu [Polish]
  • EC 201-075-4
  • EINECS 201-075-4
  • HSDB 841
  • Lead tetraethide
  • Lead, tetraethyl-
  • NCI-C54988
  • NSC 22314
  • Piombo tetra-etile
  • Piombo tetra-etile [Italian]
  • Plumbane, tetraethyl-
  • RCRA waste number P110
  • Tetra(methylethyl)lead
  • Tetraethyl lead
  • Tetraethyllead
  • Tetraethylolovo
  • Tetraethylolovo [Czech]
  • Tetraethylplumbane
  • UNII-13426ZWT6A

Systematic Names

  • Plumbane, tetraethyl-
  • Tetraethyllead

Superlist Names

  • Lead tetraethyl
  • NA1649
  • Plumbane, tetraethyl-
  • RCRA waste no. P110
  • Tetraethyl lead
  • Tetraethyl lead, liquid
  • Tetraethyl lead, liquid [NA1649] [Poison]
  • Tetraethyllead
  • Tetraethyllead, liquid

Registry Numbers

CAS Registry Number

  • 78-00-2

FDA UNII

  • 13426ZWT6A

System Generated Number

  • 0000078002

Structure Descriptors

InChI

1S/4C2H5.Pb/c4*1-2;/h4*1H2,2H3;

InChIKey

MRMOZBOQVYRSEM-UHFFFAOYSA-N

Smiles

[Pb](CC)(CC)(CC)CC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo skin 547mg/kg (547mg/kg)   Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.
guinea pig LDLo skin 995mg/kg (995mg/kg)   Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.
human TCLo inhalation 1749gm/m3/30M (1749000mg/m3) GASTROINTESTINAL: NAUSEA OR VOMITING

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 17, Pg. 223, 1975.
man LDLo unreported 1470ug/kg (1.47mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse LCLo inhalation 650mg/m3/7H (650mg/m3)   Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.
mouse LD50 subcutaneous 13020ug/kg (13.02mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
Fukuoka Igaku Zasshi. Vol. 49, Pg. 2779, 1958.
rabbit LDLo intravenous 22mg/kg (22mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rabbit LDLo oral 30mg/kg (30mg/kg)   Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.
rabbit LDLo skin 830mg/kg (830mg/kg)   Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 15, Pg. 3, 1973.
rabbit LDLo subcutaneous 32mg/kg (32mg/kg)   Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat LC50 inhalation 850mg/m3/1H (850mg/m3) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: EXCITEMENT
British Journal of Industrial Medicine. Vol. 18, Pg. 277, 1961.
rat LD50 intraperitoneal 15mg/kg (15mg/kg)   Medicina del Lavoro. Industrial Medicine. Vol. 54, Pg. 486, 1963.
rat LD50 intravenous 14400ug/kg (14.4mg/kg)   Medicina del Lavoro. Industrial Medicine. Vol. 54, Pg. 486, 1963.
rat LD50 oral 12300ug/kg (12.3mg/kg) BEHAVIORAL: AGGRESSION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Experientia. Vol. 28, Pg. 923, 1972.
rat LD50 parenteral 15mg/kg (15mg/kg)   Annals of Occupational Hygiene. Vol. 3, Pg. 226, 1961.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -1.36E+02 deg C   EXP
Boiling Point 202 deg C   EXP
log P (octanol-water) 4.15 (none)   EXP
Water Solubility 0.29 mg/L 26 EXP
Vapor Pressure 0.26 mm Hg 25 EXP
Henry's Law Constant 0.568 atm-m3/mole 24 EXP
Atmospheric OH Rate Constant 6.30E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.