|
|
Substance Name: Triparanol [INN:BAN]
RN: 78-41-1
UNII: 63S8C3RXGS
InChIKey: SYHDSBBKRLVLFF-UHFFFAOYSA-N
Note
- Antilipemic agent with high ophthalmic toxicity. According to Merck Index, 11th ed, the compound was withdrawn from the market in 1962 because of its association with the formation of irreversible cataracts.
Molecular Formula
- C27-H32-Cl-N-O2
Molecular Weight
- 438.008
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Antimetabolites
- Drug / Therapeutic Agent
- Hypolipidemic Agents
- Lipid Regulating Agents
- Reproductive Effect
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Triparanol
- Triparanol [INN:BAN]
MeSH Heading
- Triparanol
Synonyms
- 1-(4-(2-(Diethylamino)ethoxy)phenyl)-1-(p-tolyl)-2-(p-chlorophenyl)ethanol
- 1-(p-(beta-Diethylaminoethoxy)phenyl)-1-(p-tolyl)-2-(p-chlorophenyl)ethanol
- 2-(p-Chlorophenyl)-1-(p-(beta-diethylaminoethoxy)phenyl)-1-(p-tolyl)ethanol
- 2-p-Chlorophenyl-1-(p-(2-diethylaminoethoxy)phenyl)-1-p-tolylethanol
- alpha-(p-Chlorobenzyl)-4-diethylaminoethoxy-4'-methylbenzhydrol
- BRN 2064866
- EINECS 201-115-0
- MER 29
- Metasqualene
- NSC 65345
- Triparanol
- Triparanolo
- Triparanolo [DCIT]
- Triparanolum
- Triparanolum [INN-Latin]
- UNII-63S8C3RXGS
Systematic Names
- 2-p-Chlorophenyl-1-(p-(2-diethylaminoethoxy)phenyl)-1-p-tolylethanol
- Benzeneethanol, 4-chloro-alpha-(4-(2-(diethylamino)ethoxy)phenyl)-alpha-(4-methylphenyl)-
- Ethanol, 2-(p-chlorophenyl)-1-(p-(2-(diethylamino)ethoxy)phenyl)-1-p-tolyl-
- Triparanol
Registry Numbers
CAS Registry Number
- 78-41-1
FDA UNII
- 63S8C3RXGS
System Generated Number
- 0000078411
Structure Descriptors
InChI
InChI=1S/C27H32ClNO2/c1-4-29(5-2)18-19-31-26-16-12-24(13-17-26)27(30,23-10-6-21(3)7-11-23)20-22-8-14-25(28)15-9-22/h6-17,30H,4-5,18-20H2,1-3H3InChIKey
SYHDSBBKRLVLFF-UHFFFAOYSA-NSmiles
CCN(CC)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LD50 | oral | 2gm/kg (2000mg/kg) | Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 155, Pg. 2255, 1961. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 103 | deg C | EXP | |
log P (octanol-water) | 6.820 | (none) | EST | |
Atmospheric OH Rate Constant | 1.59E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.