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Substance Name: Carisoprodol [USP:INN:BAN]
RN: 78-44-4
UNII: 21925K482H
InChIKey: OFZCIYFFPZCNJE-UHFFFAOYSA-N
Note
- A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202).
Molecular Formula
- C12-H24-N2-O4
Molecular Weight
- 260.332
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Central Nervous System Agents
- Drug / Therapeutic Agent
- Muscle Relaxants, Central
- Neuromuscular Agents
- Peripheral Nervous System Agents
- Relaxant (Skeletal Muscle)
- Reproductive Effect
- Tumor Data
Superlist Classification Code
- DEA Schedule IV
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Names and Synonyms
Name of Substance
- Carisoprodol
- Carisoprodol [USP:INN:BAN]
MeSH Heading
- Carisoprodol
Synonyms
- (+-)-2-Methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate
- (1-Methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester
- 1,3-Propanediol, 2-methyl-2-propyl-, carbamate isopropylcarbamate (ester)
- 2-Methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate
- 4-04-00-00520 (Beilstein Handbook Reference)
- Apesan
- Artifar
- Arusal
- Atonalyt
- Brianil
- BRN 1791537
- Calenfa
- Caprodat
- Carbamic acid, ester with 2-(hydroxymethyl)-2-methylpentyl isopropylcarbamate
- Carbamic acid, ester with 2-methyl-2-propyl-1,3-propanediol isopropylcarbamate
- Carbamic acid, isopropyl-, 2-(hydroxymethyl)-2-methylpentyl ester carbamate (ester)
- Caridolin
- Carisol
- Carisoma
- Carisoprodate
- Carisoprodatum
- Carisoprodol
- Carisoprodolo
- Carisoprodolo [DCIT]
- Carisoprodolum
- Carisoprodolum [INN-Latin]
- Carlsodol
- Carlsoma
- Carlsoprol
- Carsodal
- Carsodol
- CB 8019
- CCRIS 4764
- Chinchen
- Diolene
- Domarax
- EINECS 201-118-7
- Fibrosona
- Flexagilt
- Flexagit
- Flexal
- Flexartal
- Flexidon
- HSDB 3021
- Isobamate
- Isomeprobamate
- Isopropyl meprobamate
- Isopropylcarbamic acid, ester with 2-(hydroxymethyl)-2-methylpentyl carbamate
- Isoprotan
- Isoprotane
- Isoprothane
- Izoprotan
- Listaflex
- Mediquil
- Meprodat
- Mioartrina
- Miolisodal
- Mioratrina
- Mioril
- Mioriodol
- Muslax
- N-Isopropyl-2-methyl-2-propyl-1,3-propanediol dicarbamate
- NCI-C56235
- Neotica
- Nospasm
- NSC 172124
- Prazolamine
- Rela
- Relasom
- Sanoma
- Sch 7307
- Scutamil-C
- Skutamil
- Soma
- Somadril
- Somalgit
- Somanil
- Stialgin
- Tonolyt isopropyl meprobamate
- UNII-21925K482H
Systematic Names
- 2-Methyl-2-propyl-1,3-propanediol carbamate isopropylcarbamate
- Carbamic acid, (1-methylethyl)-, 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester
- Carbamic acid, isopropyl-, 2-(hydroxymethyl)-2-methylpentyl ester carbamate (ester)
- Carisoprodol
Superlist Names
- Carisoprodol
- DEA No. 8192
Registry Numbers
CAS Registry Number
- 78-44-4
FDA UNII
- 21925K482H
Other Registry Number
- 8053-63-2
System Generated Number
- 0000078444
Structure Descriptors
InChI
InChI=1S/C12H24N2O4/c1-5-6-12(4,7-17-10(13)15)8-18-11(16)14-9(2)3/h9H,5-8H2,1-4H3,(H2,13,15)(H,14,16)InChIKey
OFZCIYFFPZCNJE-UHFFFAOYSA-NSmiles
CCCC(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 800mg/kg (800mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 238, Pg. 92, 1960. | |
mouse | LD50 | intravenous | 165mg/kg (165mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 127, Pg. 66, 1959. |
mouse | LD50 | oral | 1800mg/kg (1800mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 340, 1962. |
rabbit | LD50 | intravenous | 124mg/kg (124mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: REGIDITY BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) | International Journal of Neuropharmacology. Vol. 5, Pg. 305, 1966. |
rat | LD50 | intraperitoneal | 450mg/kg (450mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE | Journal of Pharmacology and Experimental Therapeutics. Vol. 127, Pg. 66, 1959. |
rat | LD50 | intravenous | 450mg/kg (450mg/kg) | Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963. | |
rat | LD50 | oral | 1320mg/kg (1320mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE | Journal of Pharmacology and Experimental Therapeutics. Vol. 127, Pg. 66, 1959. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 92 | deg C | EXP | |
log P (octanol-water) | 2.360 | (none) | EST | |
Water Solubility | 300 | mg/L | 25 | EXP |
Atmospheric OH Rate Constant | 3.42E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.