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Substance Name: Methyl ethyl ketone
RN: 78-93-3
UNII: 6PT9KLV9IO
InChIKey: ZWEHNKRNPOVVGH-UHFFFAOYSA-N

Note

  • Solvent; colorless synthetic resins, smokeless powders; may be irritating to eyes, mucous membranes; may be toxic in high concentrations.

Molecular Formula

  • C4-H8-O

Molecular Weight

  • 72.1062
 

Classification Codes

Classification Codes

  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 208
  • 2011 CERCLA Priority List, Rank: 212
  • Reportable Quantity (RQ) = 5000 lb
  • TWA (200 ppm); STEL (300 ppm); BEI
  • TWA 200 ppm (590 mg/m3)

Names and Synonyms

Name of Substance

  • 2-Butanone
  • MEK
  • Methyl ethyl ketone
  • Methylethyl ketone

Synonyms

  • 2-Butanone
  • 3-Butanone
  • Acetone, methyl-
  • Aethylmethylketon
  • Aethylmethylketon [German]
  • AI3-07540
  • AI3-07540 (USDA)
  • Butanone 2
  • Butanone 2 [French]
  • Caswell No. 569
  • CCRIS 2051
  • EC 201-159-0
  • EINECS 201-159-0
  • EPA Pesticide Chemical Code 044103
  • Ethyl methyl cetone
  • Ethyl methyl cetone [French]
  • Ethyl methyl ketone
  • Ethylmethylcetone
  • Ethylmethylcetone [French]
  • Ethylmethylketon
  • Ethylmethylketon [Dutch]
  • FEMA No. 2170
  • HSDB 99
  • Ketone, ethyl methyl
  • Meetco
  • MEK
  • Methyl acetone
  • Methyl ethyl ketone
  • Methylethyl ketone
  • Methylethylketone
  • Metiletilcetona
  • Metiletilcetona [Spanish]
  • Metiletilchetone
  • Metiletilchetone [Italian]
  • Metyl ethyl ketone
  • Metyloetyloketon
  • Metyloetyloketon [Polish]
  • RCRA waste number U159
  • UNII-6PT9KLV9IO

Systematic Names

  • 2-Butanone
  • Butanone
  • Methyl ethyl ketone

Superlist Names

  • 2-Butanone
  • Ethyl methyl ketone or methyl ethyl ketone
  • Ethyl methyl ketone or methyl ethyl ketone [UN1193] [Flammable liquid]
  • MEK
  • Methyl ethyl ketone
  • RCRA waste no. U159
  • UN1193

Registry Numbers

CAS Registry Number

  • 78-93-3

FDA UNII

  • 6PT9KLV9IO

Other Registry Number

  • 135311-02-3

System Generated Number

  • 0000078933

Structure Descriptors

InChI

InChI=1S/C4H8O/c1-3-4(2)5/h3H2,1-2H3

InChIKey

ZWEHNKRNPOVVGH-UHFFFAOYSA-N

Smiles

CCC(=O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intraperitoneal 2gm/kg (2000mg/kg)   Food and Cosmetics Toxicology. Vol. 15, Pg. 627, 1977.
guinea pig LDLo intraperitoneal 2gm/kg (2000mg/kg) LIVER: OTHER CHANGES Food and Cosmetics Toxicology. Vol. 15, Pg. 627, 1977.
human TCLo inhalation 100ppm/5M (100ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION		 Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.
mammal (species unspecified) LC50 inhalation 38gm/m3 (38000mg/m3)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.
mouse LC50 inhalation 32gm/m3/4H (32000mg/m3)   Current Toxicology. Vol. 1, Pg. 47, 1993.
mouse LD50 intraperitoneal 616mg/kg (616mg/kg)   Shell Chemical Company. Unpublished Report. Vol. -, Pg. 6, 1961.
mouse LD50 oral 4050mg/kg (4050mg/kg)   Toxicology Letters. Vol. 30, Pg. 13, 1986.
rabbit LD50 skin 6480mg/kg (6480mg/kg)   Shell Chemical Company. Vol. MSDS-5390-4,
rat LC50 inhalation 23500mg/m3/8H (23500mg/m3)   American Industrial Hygiene Association Journal. Vol. 20, Pg. 364, 1959.
rat LD50 intraperitoneal 607mg/kg (607mg/kg)   Environmental Research. Vol. 40, Pg. 411, 1986.
rat LD50 oral 2737mg/kg (2737mg/kg)   Toxicology and Applied Pharmacology. Vol. 19, Pg. 699, 1971.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -8.66E+01 deg C   EXP
Boiling Point 79.5 deg C   EXP
pKa Dissociation Constant 14.7 (none) 25 EXP
log P (octanol-water) 0.29 (none)   EXP
Water Solubility 2.23E+05 mg/L 25 EXP
Vapor Pressure 90.6 mm Hg 25 EXP
Henry's Law Constant 5.69E-05 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.15E-12 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.