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Substance Name: Pimagedine [INN]
RN: 79-17-4
UNII: SCQ4EZQ113
InChIKey: HAMNKKUPIHEESI-UHFFFAOYSA-N

Note

  • Diamine oxidase & nitric oxide synthase inhibitor; an advanced glycosylation end product inhibitor; used in the treatment of diabetic complications.

Molecular Formula

  • C-H6-N4

Molecular Weight

  • 74.0864
 

Classification Code

  • Enzyme Inhibitors
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Names and Synonyms

Name of Substance

  • Pimagedine
  • Pimagedine [INN]

Synonyms

  • Aminate base
  • Aminoguanidine
  • CCRIS 3511
  • EINECS 201-183-1
  • Guanyl hydrazine
  • Imino semicarbazide
  • Monoaminoguanidine
  • Pimagedine
  • UNII-SCQ4EZQ113

Systematic Names

  • Aminoguanidine
  • Guanidine, amino-
  • Hydrazinecarboximidamide (9CI)

Registry Numbers

CAS Registry Number

  • 79-17-4

FDA UNII

  • SCQ4EZQ113

Related Registry Number

  • 1937-19-5 (hydrochloride)

System Generated Number

  • 0000079174

Structure Descriptors

InChI

1S/CH6N4/c2-1(3)5-4/h4H2,(H4,2,3,5)

InChIKey

HAMNKKUPIHEESI-UHFFFAOYSA-N

Smiles

C(NN)(N)=N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 963mg/kg (963mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 119, Pg. 444, 1957.
rat LD50 subcutaneous 1258mg/kg (1258mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 119, Pg. 444, 1957.