Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Homatropine methylbromide [USP:INN:BAN]
RN: 80-49-9
UNII: 68JRS2HC1C
InChIKey: FUFVKLQESJNNAN-RIMUKSHESA-M

Classification Codes

  • Anticholinergic
  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H24-N-O3.Br

Molecular Weight

  • 370.2846
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Homatropine methylbromide
  • Homatropine methylbromide [USP:INN:BAN]

Synonyms

  • 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate
  • 3alpha-Hydroxy-8-methyl-1alphaH,5alphaH-tropanium bromide mandelate
  • 8-Azoniabicyclo(3.2.1)octane, 3-((hydroxyphenylacetyl)oxy)-8,8-dimethyl-, bromide, endo-
  • 8-Methylhomatropinium bromide
  • Arkitropin
  • Camatropine
  • EINECS 201-284-0
  • Equipin
  • Esopin
  • Homapin
  • Homapin-10
  • Homapin-5
  • Homatromide
  • Homatropine methylbromide
  • Homatropini methylbromidum
  • Homatropini methylbromidum [INN-Latin]
  • Malcotran
  • Mesopin
  • Methylbromure d'homatropine
  • Methylbromure d'homatropine [INN-French]
  • Methylhomatropine bromide
  • Methylhomatropinum bromatum
  • Metilbromuro de homatropina
  • Metilbromuro de homatropina [INN-Spanish]
  • Novatrin
  • Novatrine
  • Novatropine
  • NSC 34399
  • Omatropina metilbromuro
  • Omatropina metilbromuro [DCIT]
  • Sed-Tems
  • Sethyl
  • Tropinium methobromide mandelate
  • UNII-68JRS2HC1C

Systematic Names

  • 8-Azoniabicyclo(3.2.1)octane, 3-((2-hydroxy-2-phenylacetyl)oxy)-8,8-dimethyl-, bromide (1:1), (3-endo)-
  • 8-Azoniabicyclo(3.2.1)octane, 3-((hydroxyphenylacetyl)oxy)-8,8-dimethyl-, bromide, (3-endo)-
  • 8-Azoniabicyclo(3.2.1)octane, 3-((hydroxyphenylacetyl)oxy)-8,8-dimethyl-, bromide, endo-
  • Homatropine methylbromide
  • Homatropinium, 8-methyl-, bromide

Mixture Names

  • Hycodan
  • Probilagol

Registry Numbers

CAS Registry Number

  • 80-49-9

FDA UNII

  • 68JRS2HC1C

Other Registry Numbers

  • 1786394-41-9
  • 42522-67-8
  • 55198-66-8
  • 58725-74-9

System Generated Number

  • 0000080499

Molecular Formulas

Molecular Formula

  • C17-H24-N-O3.Br

Molecular Formula Fragments

  • Br
  • C17-H24-N-O3
  • COMPONENT

Structure Descriptors

InChI

1S/C17H24NO3.BrH/c1-18(2)13-8-9-14(18)11-15(10-13)21-17(20)16(19)12-6-4-3-5-7-12;/h3-7,13-16,19H,8-11H2,1-2H3;1H/q+1;/p-1/t13-,14+,15+,16?;

InChIKey

FUFVKLQESJNNAN-RIMUKSHESA-M

Smiles

C[N+]1([C@@H]2CC[C@H]1C[C@H](C2)OC(=O)C(c3ccccc3)O)C.[Br-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 120mg/kg (120mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
guinea pig LD50 oral 1gm/kg (1000mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
guinea pig LD50 subcutaneous 75mg/kg (75mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 137, Pg. 375, 1962.
mouse LD50 intraperitoneal 60mg/kg (60mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
mouse LD50 oral 1400mg/kg (1400mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
mouse LD50 subcutaneous 130mg/kg (130mg/kg)   French Demande Patent Document. Vol. #2035763,
rat LD50 intraperitoneal 82mg/kg (82mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
rat LD50 intravenous 12mg/kg (12mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 236, Pg. 149, 1959.
rat LD50 oral 1200mg/kg (1200mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
rat LD50 subcutaneous 800mg/kg (800mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.