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Substance Name: Benzalkonium chloride [INN:BAN:JAN:NF]
RN: 8001-54-5
UNII: F5UM2KM3W7

Note

  • A mixture of alkylbenzyldimethylammonium compounds. It is a bactericidal quaternary ammonium detergent used topically in medicaments, deodorants, mouthwashes, as a surgical antiseptic, and as a as preservative and emulsifier in drugs and cosmetics.

Molecular Formula

  • Unspecified

Molecular Weight

  • 170.662
 

Classification Codes

  • Agricultural Chemical
  • Anti-Infective Agents
  • Anti-Infective Agents, Local
  • Detergents
  • Drug / Therapeutic Agent
  • Fungicide, Bactericide, Wood Preservative
  • Germicide, Bactericide, Disinfectant
  • Herbicide
  • Human Data
  • Mutation Data
  • Pharmaceutic Aid (Preservative)
  • Pharmaceutic Aids
  • Preservatives, Pharmaceutical
  • Reproductive Effect
  • Skin / Eye Irritant
  • Surface-Active Agents

Names and Synonyms

Name of Substance

  • Benzalkonium chloride compounds
  • Benzalkonium chloride [INN:BAN:JAN:NF]

MeSH Heading

  • Benzalkonium Compounds

Synonyms

  • Alkyl dimethylbenzyl ammonium chloride
  • Alkylbenzyldimethylammonium chloride
  • Alkyldimethyl(phenylmethyl)quaternary ammonium chlorides
  • Alkyldimethylbenzylammonium chloride
  • Ammonium, alkyldimethylbenzyl-, chloride
  • Ammonyx
  • Arquad B 100
  • Arquad dmmcb-75
  • BAK
  • Barquat MB-50
  • Barquat MB-80
  • Bayclean
  • Benirol
  • Benzalconio cloruro
  • Benzalconio cloruro [DCIT]
  • Benzalkonii chloridum
  • Benzalkonii chloridum [INN-Latin]
  • Benzalkonium A
  • Benzalkonium chloride
  • Bio-quat 50-24
  • Bio-quat 50-25
  • Bio-quat 50-30
  • Bio-quat 50-40
  • Bio-quat 50-42
  • Bio-quat 50-60
  • Bio-quat 50-65
  • Bio-quat 80-24
  • Bio-quat 80-28
  • Bio-quat 80-40
  • Bio-quat 80-42
  • Bionol
  • BTC 100
  • BTC 2565
  • BTC 471
  • BTC 50
  • BTC 50 USP
  • BTC 65
  • BTC 65 USP
  • BTC 824
  • BTC 8248
  • BTC 8249
  • BTC E-8358
  • Capitol
  • CCRIS 9229
  • Cequartyl
  • Chlorure de benzalkonium
  • Chlorure de benzalkonium [INN-French]
  • Cloruro de benzalconio
  • Cloruro de benzalconio [INN-Spanish]
  • Culversan LC 80
  • Desitin Dabaways
  • Desitin Skin Care Lotions
  • Dimanin A
  • Disinall
  • Dodigen 226
  • Drapolene
  • Drapolex
  • Drest
  • E-Pilo Ophthalmic Solution
  • Enuclen
  • EPA Pesticide Chemical Code 069105
  • Epifrin Ophthalmic Solution
  • Gardiquart SV480
  • Gardiquat 1450
  • Genamin KDS
  • Germ-I-tol
  • Germicin
  • Germinol
  • Germitol
  • HSDB 234
  • Hyamine 3500
  • Intexan LB-50
  • Kemamine BAC
  • Leda benzalkonium chloride
  • Mefarol
  • Murine For The Eyes
  • Muro Tears Ophthalmic Solution
  • Muro's Opcon A Ophthalmic Solution
  • Muro's Opcon Ophthalmic Solution
  • Murocoll-19 Opthalmic Solution
  • Murocoll-2 Ophthalmic Solution
  • Neo Germ-I-tol
  • Onyx BTC (Onyx oil & chem Co)
  • Osvan
  • Paralkan
  • Pheneene germicidal solution & tincture
  • Pheneene germicidal solution and tincture
  • Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
  • Quaternium-1
  • Roccal
  • Romergal CB
  • Sentry HC hotspot
  • Triton K-60
  • UNII-F5UM2KM3W7
  • Vikrol RQ
  • Visalens Soaking/Cleaning Solutions
  • Visalens Wetting Solution
  • Visine AC
  • Zephiral
  • Zephiran
  • Zephiran chloride

Systematic Names

  • Ammonium, alkyldimethyl(phenylmethyl)-, chloride
  • Ammonium, alkyldimethylbenzyl-, chloride
  • Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides

Superlist Name

  • Alkyl dimethyl ethylbenzyl ammonium chloride

Mixture Names

  • Enuclene
  • Sporostacin

Registry Numbers

CAS Registry Number

  • 8001-54-5

FDA UNII

  • F5UM2KM3W7

Other Registry Numbers

  • 12741-06-9
  • 39434-18-9
  • 59890-14-1
  • 75635-12-0
  • 8011-91-4
  • 8036-90-6
  • 8039-63-2
  • 8045-21-4

System Generated Number

  • 0008001545

Structure Descriptors

Smiles

c1(C[N+](C)(C)*)ccccc1.[ClH-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 subcutaneous 64mg/kg (64mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 219, 1970.
rat LD50 intraperitoneal 14500ug/kg (14.5mg/kg) BEHAVIORAL: ATAXIA

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 219, 1970.
rat LD50 intravenous 13900ug/kg (13.9mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 219, 1970.
rat LD50 oral 240mg/kg (240mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)		 Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 219, 1970.
rat LD50 subcutaneous 400mg/kg (400mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 219, 1970.
women TDLo oral 266mg/kg (266mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: CHANGE IN STRUCTURE OR FUNCTION OF ESOPHAGUS		 Human Toxicology. Vol. 7, Pg. 191, 1988.