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Substance Name: Mestranol mixture with Norethindrone
RN: 8015-29-0
InChIKey: HFFGOURGAIOQBU-FOWHCLFSSA-N

Note

  • Ethynylestradiol 3-methyl ether (MESTRANOL) and 17-alpha-ethynyl-19-nortestosterone mixture (NORETHINDRONE).

Molecular Formula

  • C21-H26-O2.C20-H26-O2

Molecular Weight

  • 608.8578
 

Classification Codes

  • Contraceptive Agents
  • Contraceptive Agents, Female
  • Contraceptives, Oral
  • Contraceptives, Oral, Combined
  • Drug / Therapeutic Agent
  • Hormone
  • Human Data
  • Reproductive Control Agents
  • Reproductive Effect
  • Tumor Data
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Names and Synonyms

Results Name

  • Mestranol mixture with Norethindrone

Name of Substance

  • Norinyl

Synonyms

  • 17-alpha-Ethynyl-17-hydroxyestren-3-one and ethynylestradiol 3-methyl ether
  • 17-alpha-Ethynyl-19-nortestosterone and ethynylestradiol 3-methyl ether
  • Conlumin
  • Conlunett
  • Conluten
  • Ethynylestradiol 3-methyl ether and 17-alpha-ethynyl-17-hydroxyestren-3-one
  • Ethynylestradiol 3-methyl ether and 17-alpha-ethynyl-19-nortestosterone
  • Ethynylestradiol methyl ether and norethindrone
  • Maya
  • Mestranol mixed with norethindrone
  • Mestranol mixed with norethisterone
  • Necon
  • Norethin 1/50m-21
  • Norethin 1/50m-28
  • Norethindrone - mestranol mixture
  • Norethindrone and ethynylestradiol methyl ether
  • Norethindrone and mestranol
  • Norethindrone mixed with mestranol
  • Norethindrone-mestranol
  • Norethindrone-mestranol mixture
  • Norethisterone mixed with mestranol
  • Noriday
  • Norinyl
  • Norinyl 1 50
  • Norinyl 1+50 21-day
  • Norinyl 1+50 28-day
  • Norinyl 1+80 21-day
  • Norinyl 1+80 28-day
  • Norinyl 1/50
  • Norinyl-1
  • Norluten D
  • Ortho-Novin
  • Ortho-Novum
  • Ortho-Novum 1/50 21
  • Ortho-Novum 1/50 28
  • Ortho-Novum 1/80 21
  • Ortho-Novum 1/80 28
  • Ortho-Novum 10-21
  • Ortho-Novum 2-21
  • Ortho-Novum SQ
  • Otho-Novinn
  • Sophia

Systematic Names

  • 19-Nor-17-alpha-pregn-4-en-20-yn-3-one, 17-hydroxy- mixed with 3-methoxy-19-nor-17-alpha-pregna-1,3,5(10)-trien-20-yn-17-ol
  • 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)-, mixt. with (17alpha)-3-methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17-ol

Registry Numbers

CAS Registry Number

  • 8015-29-0

Other Registry Numbers

  • 8067-96-7
  • 8068-40-4

System Generated Number

  • 0008015290

Molecular Formulas

Molecular Formula

  • C21-H26-O2.C20-H26-O2

Molecular Formula Fragments

  • C20-H26-O2
  • C21-H26-O2
  • COMPONENT

Structure Descriptors

InChI

1S/C21H26O2.C20H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17(18)9-11-20(19,21)2;1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3;1,12,15-18,22H,4-11H2,2H3/t17-,18-,19+,20+,21+;15-,16+,17+,18-,19-,20-/m10/s1

InChIKey

HFFGOURGAIOQBU-FOWHCLFSSA-N

Smiles

C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CC[C@]2(C#C)O)OC.C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 10mg/kg/Y-I (10mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING
Lancet. Vol. 1, Pg. 1479, 1973.