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Substance Name: Complement C5a
RN: 80295-54-1

Note

  • The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION.

Molecular Formula

  • Unspecified
 

Classification Code

  • Immunologic Factors
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Names and Synonyms

MeSH Heading

  • Complement C5a

Synonym

  • Anaphylatoxin C5a

Systematic Name

  • Complement C5a

Registry Numbers

CAS Registry Number

  • 80295-54-1

System Generated Number

  • 0080295541