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Substance Name: NSC 181928
RN: 80434-77-1
InChIKey: KNHPZFQUZAMWBV-UHFFFAOYSA-N

Note

  • Potently stimulates tubulin-dependent GTP hydrolysis; member of 1-deaza-7,8-dihydropteridine class of mitotic inhibitors with antineoplastic activity.

Classification Code

  • Mutation Data

Molecular Formula

  • C18-H22-N6-O2

Molecular Weight

  • 354.4118
 
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Names and Synonyms

Name of Substance

  • NSC 181928

Synonyms

  • BRN 5151945
  • Ethyl 5-amino-1,2-dihydro-3-((N-methylanilino)methyl)pyrido(3,4-b)pyrazin-7-yl carbamate
  • NSC 181928

Systematic Names

  • Carbamic acid, (5-amino-1,2-dihydro-3-((methylphenylamino)methyl)pyrido(3,4-b)pyrazin-7-yl)-, ethyl ester
  • Pyrido(3,4-b)pyrazine-7-carbamic acid, 1,2-dihydro-5-amino-3-((N-methylanilino)methyl)-, ethyl ester

Registry Numbers

CAS Registry Number

  • 80434-77-1

System Generated Number

  • 0080434771

Structure Descriptors

InChI

1S/C18H22N6O2/c1-3-26-18(25)23-15-9-14-16(17(19)22-15)21-12(10-20-14)11-24(2)13-7-5-4-6-8-13/h4-9,20H,3,10-11H2,1-2H3,(H3,19,22,23,25)

InChIKey

KNHPZFQUZAMWBV-UHFFFAOYSA-N

Smiles

CCOC(=O)Nc1cc2c(c(n1)N)N=C(CN2)CN(C)c3ccccc3