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Substance Name: Ethinyl estradiol mixture with norgestrel
RN: 8056-51-7
InChIKey: ORKBYCQJWQBPFG-WOMZHKBXSA-N

Note

  • ETHINYL ESTRADIOL and NORGESTREL given in fixed proportions. It has proved to be an effective contraceptive (CONTRACEPTIVES, ORAL, COMBINED).

Molecular Formula

  • C21-H28-O2.C20-H24-O2

Molecular Weight

  • 608.8578
 

Classification Codes

  • Contraceptive Agents
  • Contraceptive Agents, Female
  • Contraceptives, Oral
  • Contraceptives, Oral, Combined
  • Contraceptives, Oral, Synthetic
  • Contraceptives, Postcoital
  • Contraceptives, Postcoital, Synthetic
  • Drug / Therapeutic Agent
  • Hormone
  • Human Data
  • Reproductive Control Agents
  • Reproductive Effect
  • Tumor Data
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Names and Synonyms

Results Name

  • Ethinyl estradiol mixture with norgestrel

Name of Substance

  • Ethinyl estradiol-norgestrel combination

MeSH Heading

  • Ethinyl estradiol-norgestrel combination

Synonyms

  • Biphasil
  • CCRIS 7261
  • Cryselle
  • dl-Norgestrel mixed with ethinylestradiol
  • Duoluton
  • Ediwal
  • Elifemme
  • Ethinyl estradiol mixed with norgestrel
  • Ethinylestradiol mixed with dl-norgestrel
  • Ethinyloestradiol mixed with norgestrel
  • Eugynon
  • Eugynon 30
  • Femenal
  • Follimin
  • Follinett
  • Follinyl
  • Gravistat
  • Lo-Femenal
  • Lo/Ovral
  • LO/Ovral-28
  • low-ogestrel
  • Low-Ogestrel-21
  • Low-Ogestrel-28
  • Microgynon
  • Microvlar 30
  • Minidril
  • Minigynon
  • Neogynon
  • Neovletta
  • Nordiol
  • Nordiol-28
  • Norgestrel and Ethinyl Estradiol
  • Norgestrel mixed with ethinyl estradiol
  • Norgestrel mixed with ethinyloestradiol
  • Norgestrel-ethinyl estradiol
  • Norgestrel-ethynylestradiol mixt.
  • Ogestrel 0.5/50-21
  • Ogestrel 0.5/50-28
  • Orasecron
  • Ovidon
  • Ovral
  • Ovral 21
  • Ovral 28
  • Ovral L
  • Ovral-28
  • Ovran
  • Ovranett
  • Primovlar
  • Pro-Duosterone
  • Rigevidon
  • Sequilar
  • Sequilarum
  • Sequostat
  • SH 71121
  • SH D00264A
  • SHB 261AB
  • SHB 264AB
  • Stediril
  • Stediril D
  • Triquilar
  • WL 20
  • WL 33
  • WY-E 104

Systematic Names

  • 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17-alpha)-(+-)-, mixt. with (17-alpha)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol
  • Ovral

Registry Numbers

CAS Registry Number

  • 8056-51-7

Other Registry Numbers

  • 70208-30-9
  • 8063-84-1
  • 8064-50-4

System Generated Number

  • 0008056517

Molecular Formulas

Molecular Formula

  • C21-H28-O2.C20-H24-O2

Molecular Formula Fragments

  • C20-H24-O2
  • C21-H28-O2
  • COMPONENT

Structure Descriptors

InChI

1S/C21H28O2.C20H24O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2;1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h2,13,16-19,23H,3,5-12H2,1H3;1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17+,18+,19-,20-,21-;16-,17-,18+,19+,20+/m01/s1

InChIKey

ORKBYCQJWQBPFG-WOMZHKBXSA-N

Smiles

CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34.C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CC[C@]2(C#C)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral > 5500mg/kg (5500mg/kg)   Drugs in Japan Vol. 6, Pg. 567, 1982.
rat LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 567, 1982.