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Substance Name: Meglumine diatrizoate mixture with sodium diatrizoate
RN: 8064-12-8
InChIKey: XZNXVSDNACTASG-RZNNTOFGSA-M

Note

  • Urovision contains a mixture of sodium & meglumine salts of diatrizoic acid in the ratio of 50:18 in aqueous solution used in urography.

Classification Codes

  • Contrast Media
  • Diagnostic Uses of Chemicals
  • Drug / Therapeutic Agent

Molecular Formula

  • C11-H9-I3-N2-O4.C11-H8-I3-N2-O4.C7-H17-N-O5.Na

Molecular Weight

  • 1445.0
 
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Names and Synonyms

Results Name

  • Meglumine diatrizoate mixture with sodium diatrizoate

Name of Substance

  • Meglumine diatrizoate mixture with sodium diatrizoate
  • Meglumine sodium amidotrizoate injection [JAN]
  • Urovision

Synonyms

  • Angiovist 292
  • Angiovist 370
  • Diatrizoate de sodium et de methylglucamine
  • Diatrizoate de sodium et de methylglucamine [French]
  • Diatrizoate meglumine and diatrizoate sodium
  • Gastrografin
  • Hypaque
  • Hypaque 75M
  • Hypaque 76
  • Hypaque 85
  • Hypaque M 380
  • Hypaque-M
  • MD 76
  • MD-76r
  • MD-Gastroview
  • Meglumine sodium amidotrizoate
  • Meglumine sodium amidotrizoate injection
  • Penografin-76
  • Pielografin
  • Radioselectan 76
  • Radioselectan forte
  • RenoCal 76
  • Renocal-76
  • Renografin 60
  • Renografin 76
  • Renografin-60
  • Renovist
  • Renovist II
  • Sodium meglumine diatrizoate
  • Sodium methylglucamine diatrizoate
  • Trazograph
  • Triobrast
  • Triombrast
  • Triyosom C
  • Urografin
  • Urografin 290
  • Urografin 325
  • Urografin 60
  • Urografin 76
  • Urombrine 420
  • Uropoline
  • Uropolinum
  • Urovison
  • Vascovue 76
  • Verografin
  • Verographin
  • Visotrast

Systematic Name

  • D-Glucitol, 1-deoxy-1-(methylamino)-, 3,5-bis(acetylamino)-2,4,6-triiodobenzoate (salt) mixed with 3,5-bis(acetylamino)-2,4,6-triiodobenzoic acid monosodium salt

Registry Numbers

CAS Registry Number

  • 8064-12-8

Other Registry Numbers

  • 102341-28-6
  • 118625-39-1
  • 16998-52-0
  • 18702-56-2
  • 19121-26-7
  • 39468-26-3
  • 51745-36-9
  • 519-27-7
  • 63705-10-2
  • 78171-11-6
  • 8060-83-1
  • 8065-19-8
  • 8065-20-1

System Generated Number

  • 0008064128

Molecular Formulas

Molecular Formula

  • C11-H9-I3-N2-O4.C11-H8-I3-N2-O4.C7-H17-N-O5.Na

Molecular Formula Fragments

  • C11-H8-I3-N2-O4
  • C11-H9-I3-N2-O4
  • C7-H17-N-O5
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/2C11H9I3N2O4.C7H17NO5.Na/c2*1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;1-8-2-4(10)6(12)7(13)5(11)3-9;/h2*1-2H3,(H,15,17)(H,16,18)(H,19,20);4-13H,2-3H2,1H3;/q;;;+1/p-1/t;;4-,5+,6+,7+;/m..0./s1

InChIKey

XZNXVSDNACTASG-RZNNTOFGSA-M

Smiles

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.c1(I)c(c(I)c(c(c1NC(C)=O)I)C([O-])=O)NC(=O)C.c1(c(c(c(c(c1NC(C)=O)I)C(=O)O)I)NC(=O)C)I.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 11500mg/kg (11500mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Therapie. Vol. 26, Pg. 595, 1971.
mouse LD50 unreported 22525mg/kg (22525mg/kg)   Farmatsiya Vol. 32(3), Pg. 18, 1983.
rat LD50 intravenous 29200ug/kg (29.2mg/kg) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 12(Suppl,
rat LD50 unreported 19gm/kg (19000mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 921, 1984.