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Substance Name: Heparin cofactor II
RN: 81604-65-1


  • A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily.

Classification Codes

  • Anticoagulants
  • Antithrombins
  • Enzyme Inhibitors
  • Hematologic Agents
  • Protease Inhibitors
  • Serine Proteinase Inhibitors
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Names and Synonyms

Name of Substance

  • Heparin cofactor II

MeSH Heading

  • Heparin cofactor II

Systematic Name

  • Heparin cofactor II

Registry Numbers

CAS Registry Number

  • 81604-65-1

System Generated Number

  • 0081604651