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Substance Name: Macrophage colony-stimulating factor
RN: 81627-83-0


  • A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).

Molecular Formula

  • Unspecified

Classification Codes

  • Natural Product
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • Macrophage colony-stimulating factor

MeSH Heading

  • Macrophage colony-stimulating factor


  • Colony stimulating factor-1
  • CSF-1
  • Cytokines, macrophage colony-stimulating factor
  • Macrophage colony-stimulating factor
  • Monocyte colony-stimulating factor

Systematic Name

  • Colony-stimulating factor 1

Registry Numbers

CAS Registry Number

  • 81627-83-0

System Generated Number

  • 0081627830