Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Cotarnine
RN: 82-54-2
UNII: 79V56TDI6G
InChIKey: PAPMYQLKLNRZIR-UHFFFAOYSA-N

Molecular Formula

  • C12-H15-N-O4

Molecular Weight

  • 237.2535
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Cotarnine

Synonyms

  • 4-27-00-06448 (Beilstein Handbook Reference)
  • 5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-ol
  • BRN 0022879
  • EINECS 201-429-8
  • UNII-79V56TDI6G

Systematic Names

  • 1,3-Dioxolo(4,5-g)isoquinolin-5-ol, 5,6,7,8-tetrahydro-4-methoxy-6-methyl- (9CI)
  • 5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-ol
  • Cotarnin
  • Cotarnine

Registry Numbers

CAS Registry Number

  • 82-54-2

FDA UNII

  • 79V56TDI6G

System Generated Number

  • 0000082542

Structure Descriptors

InChI

1S/C12H15NO4/c1-13-4-3-7-5-8-10(17-6-16-8)11(15-2)9(7)12(13)14/h5,12,14H,3-4,6H2,1-2H3

InChIKey

PAPMYQLKLNRZIR-UHFFFAOYSA-N

Smiles

CN1CCc2cc3c(c(c2C1O)OC)OCO3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo unreported 200mg/kg (200mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
frog LDLo unreported 40mg/kg (40mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
mouse LDLo subcutaneous 400mg/kg (400mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Pharmazie. Vol. 15, Pg. 111, 1960.
rabbit LDLo intravenous 180mg/kg (180mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: TREMOR
Pharmazie. Vol. 15, Pg. 111, 1960.
rabbit LDLo unreported 180mg/kg (180mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 132.5 dec deg C   EXP
log P (octanol-water) 0.560 (none)   EST
Atmospheric OH Rate Constant 3.45E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.