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Substance Name: Amflutizole [USAN:INN]
RN: 82114-19-0
UNII: 83N680M457
InChIKey: KVMCEGAWQYTFKC-UHFFFAOYSA-N

Note

  • Xanthine oxidase inhibitor.

Classification Codes

  • Drug / Therapeutic Agent
  • Suppressant (gout)

Molecular Formula

  • C11-H7-F3-N2-O2-S

Molecular Weight

  • 288.248
 
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Names and Synonyms

Name of Substance

  • Amflutizole
  • Amflutizole [USAN:INN]

Synonyms

  • 4-Amino-3-(3-(trifluoromethyl)phenyl)-5-isothiazolecarboxylic acid
  • 4-Amino-3-(alpha,alpha,alpha-trifluoro-m-tolyl)-5-isothiazolecarboxylic acid
  • 5-Isothiazolecarboxylic acid, 4-amino-3-(3-(trifluoromethyl)phenyl)-
  • Amflutizol
  • Amflutizol [Spanish]
  • Amflutizole
  • Amflutizolum
  • Amflutizolum [Latin]
  • LY 141894
  • UNII-83N680M457

Systematic Name

  • 5-Isothiazolecarboxylic acid, 4-amino-3-(3-(trifluoromethyl)phenyl)-

Registry Numbers

CAS Registry Number

  • 82114-19-0

FDA UNII

  • 83N680M457

System Generated Number

  • 0082114190

Structure Descriptors

InChI

1S/C11H7F3N2O2S/c12-11(13,14)6-3-1-2-5(4-6)8-7(15)9(10(17)18)19-16-8/h1-4H,15H2,(H,17,18)

InChIKey

KVMCEGAWQYTFKC-UHFFFAOYSA-N

Smiles

c1(c2cc(ccc2)C(F)(F)F)c(c(C(O)=O)sn1)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 798mg/kg (798mg/kg)   United States Patent Document. Vol. #4346094,